Zygem Corporation Limited

Other

Lockheed Martin Corporation

Leidos Innovations Technology, Inc.

Microlab Diagnostics, Inc.

David Saul

James P Landers

Orion N Scott

Brian Root

Matthew Daniel Solomon

Joan Marie Bienvenue

Jason Paul Hayes

Douglas J South

Michael E Egan

Matthew Springer

Peter Van Ruijven

An-Chi Tsuei

Paul Kinnon

Daniel G Mills

Roy M Daniel

Jingyi Li

Christopher Birch

David Vigil

Andrew Guy

Stan Wada

Betina De Gorordo

Steward Dodman

Tom Moran

Stuart Knowles

Fernando Dias

Rick Gardner

Matthew Yeung

A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.

Method and system for sample collection, storage, preparation and detection

A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.

Microfluidic cartridge

A sample collection device suitable for low-volume extraction includes a substantially tubular collection vessel having a closed end, an open end, and one or more sidewalls defining a vessel chamber having a vessel volume. The device further includes a swab for sample collection. The swab formed with a substantially closed-celled polymer foam head and the swab is configured for insertion into the collection vessel.

Sample collection device suitable for low-volume extraction

The present invention relates to thermostable proteinases from thermophilic Bacillus species and their uses in the preparation of nucleic acid samples. The enzymes of the invention are stable and active at 65-80&#xb0; C., but are readily autolysed or denatured above 90&#xb0; C.

Thermostable proteinases from thermophilic bacteria

Growing community of inventors

Auckland, New Zealand

David Saul