Novoste Corporation

Other

Emory University

Varian Medical Systems, Inc.

David S Halpern

Richard A Hillstead

Raphael F Meloul

George K Bonnoitt, Jr

Charles E Larsen

Thomas D Weldon

Jonathan J Rosen

Ian R Crocker

Ron Waksman

Roelof Trip

Martin B Tobias

Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the intraluminal passageways of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's intraluminal passageways. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.

Method and apparatus for radiation treatment of a desired area in the vascular system of a patient

This invention is a transfer device and catheter assembly for the delivery of treatment elements to a selected location within the intraluminal passageways of a patient as part of an intraluminal radiation system. The transfer device includes a gate member that permits the treatment elements to leave the transfer device only if the catheter is attached thereto. A pressure indicator provides a visual indication of the fluid pressure within the transfer device, and a pressure relief valve provides for a release of the fluid if the pressure exceeds a predetermined pressure. Transfer device also includes a treatment element detection system, low power indicator, a counter system, and an electromagnetic locking mechanism to prevent the opening or closing of the gate member when less than all of the treatment elements are in the transfer device.

Intraluminal radiation treatment system

Catheter apparatus for radiation treatment of a desired area in the

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Alpharetta, GA, United States of America

David S Halpern