Ligand Pharmaceuticals, Inc.

Fmc Corporation

Bayer Cropscience Ag

David Rosen

Lin Zhi

Koc-Kan Ho

Brian F McGuinness

Cornelis Arjan Van Oeveren

Bijan Pedram

Jeffrey John Letourneau

David J Diller

Jason Conrad Pickens

Yixing Shen

Andrew Graham Cole

Walter H Yeager

George Theodoridis

Robert N Henrie, Ii

Stephen F Donovan

John W Lyga

Thomas G Cullen

Ariamala Gopalsamy

Inna Shulman

Ian R Silverman

Daniel H Cohen

Paul E Rensner

Ping Ding

Y Larry Zhang

Guozhi Wang

Seong Jae Yu

Dennis L Warkentin

Qun Zhang

Steven Shunxiang Zhang

Syed Z Ahmed

Stephen Shunxiang Zhang

Hongbin Men

Shunxiang Zhang

Jason C Pickens

Compounds and methods in the fields of chemistry and medicine are disclosed. Some of the disclosed embodiments include compounds, compositions and methods of using heterocycle amines. Some of the disclosed embodiments include heterocycle amines useful to treat inflammatory disorders.

Heterocycle amines and uses thereof

N-substituted azacycle derivative compounds represented by formula (I): 

N-substituted azacycles

It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines

It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is CH or N; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines

It has now been found that certain novel N-(substituted aryl)-4(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present 

Growing community of inventors

Kendall Park, NJ, United States of America

David Rosen