General Electric Company

Other

Ge Infrastructure Technology, LLC

Global Life Sciences Solutions Operations UK Ltd

University of Washington

Tokitae LLC

Amazon Technologies, Inc.

Bha Altair. LLC

Parker-hannifin Corporation

Cytiva Sweden Ab

David Roger Moore

Matthew Jeremiah Misner

Hongyi Zhou

Daniel Joseph Brunelle

John Richard Nelson

Cathryn Ellen Olsen

Joyce Hung

Marianne Elisabeth Harmon

Gregory Andrew Grossmann

Bing Li

Hongwei Liu

Daniel Jason Erno

Paul Michael Smigelski, Jr

Daniel Steiger

William Christopher Alberts

Brian Christopher Bales

Andrew Arthur Paul Burns

Vitali Victor Lissianski

Anil Raj Duggal

Patrick Joseph McCloskey

Bernhard Hans Weigl

Julia L Lee

Erik Leeming Kvam

Albert Santo Stella

Mark Daniel Doherty

Louisa Ruth Carr

Lisa Kathryn Lafleur

Joshua Davis Bishop

Maxwell Wheeler

Benjamin David Grant

John Thomas Connelly

Hieu Minh Duong

Eugene R Moore

Jon Robert Ducrou

Minglin Ma

Robert Scott Duthie

Joseph Anthony Suriano

Ryo Tamaki

Frank John Mondello

Christoph Georg Erben

Vicki Herzl Watkins

Patrick McCoy Spooner

Kevin Paul Flood Nichols

Joshua James Stone

Xiaohui Chen

Lifeng Zhang

Jason Michael Nichols

Sasha Mikhael Perez

David S Ginger

Omayra Liz Padilla De Jesus

David Michael Cate

Ryan Austin Hutchinson

Matthew F Rosen

Elizabeth Marie Dees

Joseph Louis Traub

Andrew Clive Wood

Aya Mitake

Rajiv Giridharagopal

Glennis Rayermann

Obadiah Reid

Curry L Aten

Patrick Joseph Mccloskey

Patrick Mccoy Spooner

Louise Ruth Carr

Julia Lam Lee

A carbon dioxide (CO) capture system and method for removing COfrom an inlet gas including a first fluid stream inlet providing for the flow of a first fluid stream, such as an inlet gas containing CO, and a second fluid stream inlet providing for the flow of a second fluid stream, such as steam, an outlet providing for the flow of a COdepleted stream from the COcapture system, an outlet providing for the flow of a COstream from the COcapture system and a concentrator in fluid communication with the first fluid stream. The system further including a first contactor and a second contactor. Each of the first contactor and the second contactor defining therein a first fluidically-isolated, sorbent-integrated, fluid domain for flow of the first fluid stream and COadsorption and a second fluidically-isolated fluid domain for flow of the second fluid stream to assist in desorption.

Carbon dioxide capture with system of contactors each having fluidically-isolated, thermally-connected, parallel fluid domains

A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet. The at least one contactor defining therein a first fluidically-isolated, sorbent-integrated, fluid domain for flow of the first fluid stream and water adsorption, a second fluidically-isolated fluid domain for flow of the second fluid stream wherein the second fluidically-isolated fluid domain is in thermal communication with the first fluidically-isolated, sorbent-integrated, fluid domain and a third fluidically-isolated fluid domain for capture of a condensate and recycling of latent heat of condensation back to the first fluidically-isolated, sorbent-integrated, fluid domain.

Water recovery system including integrated contactor with thermally-enhanced recovery

Carbon dioxide capture system and method of capturing carbon dioxide

A device comprising a modified porous membrane is provided. The modified porous membrane comprises a polymer coating grafted to a porous membrane. The device is used for analyte detection from a biological sample using an immunoassay. The device comprises a sample application zone at one end of the device for applying a biological sample comprising a target analyte; and a detection zone present at another end of the device, downstream of the sample application zone for detecting the target analyte, wherein the detection zone comprises one or more first biomolecules immobilized on a modified porous membrane having a structure of Formula (I).

Porous membranes with a polymer grafting, methods and uses thereof

A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.

Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity

A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2&#xd7; to 25&#xd7; compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.

Method and associated device for rapid detection of target biomolecules with enhanced sensitivity

An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.

Electrospun fibers for protein stabilization and storage

The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region. The sample assessment device may also include a valve coupled to the substrate and configured to separate the amplification region from the detection region in a closed configuration, wherein the amplification region and the valve are positioned on the sample assessment device between the sample application region and the detection region and wherein the sample assessment device is configured to permit lateral flow from the amplification region to the detection region when the valve is in an open configuration.

Amplification and detection of nucleic acids

A rapid diagnostic testing device for testing of a biological sample is provided. The device comprises a channeled construct, at least one lateral flow unit, and a cassette housing. The channeled construct is configured to receive a biological sample to form at least partially purified biological sample. The lateral flow unit is at least partially disposed in the cassette housing. The lateral flow unit comprises: a sample receiving zone, a conjugate zone and a detection zone. The sample receiving zone is operatively coupled to the channeled construct for receiving the partially purified biological sample comprising at least one analyte. The conjugate zone comprising a conjugate particle to bind the analyte is disposed adjacent to the first side of the sample receiving zone. The detection zone is disposed adjacent to the second side of the sample receiving zone and comprises at least one binding agent for detecting the analyte.

Device for rapid diagnostic tests to detect antigens with improved sensitivity

A membrane including a block copolymer is presented. The block copolymer includes at least one block A including structural units having a formula (I), and at least one block B including structural units having a formula (II). A hollow-fiber membrane for hemodialysis or hemofiltration, and associated block copolymer are also presented.

Zwitterion-functionalized block copolymer membranes and associated block copolymer composition

A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided.

Method, substrate and device for separating nucleic acids

Growing community of inventors

Rexford, NY, United States of America

David Roger Moore