Perimeter Medical Imaging, Inc.

David Rempel

James Jackson

Stephen Lewis Leckenby

Elizabeth Alice Munro

Chao Fan

Andrew Berkeley

Yaaseen Atchia

Jason Silver

Stephen Mcfayden

James Elliot Cameron

Rory Carrillo

Trevor Pleydell-Bouverie Malcolm Moat

Embodiments described herein relate to an apparatus for positioning and securing an excised biological tissue specimen for imaging and analysis. In some embodiments, an apparatus includes a sample bag defining an inner volume configured to receive a biological tissue sample, and a sealing member coupled to the sample bag. An imaging window is disposed and configured to be placed in contact with at least a portion of the biological tissue sample, and a positioning member is coupled to the imaging window and is configured to be disposed against the sealing member to substantially seal the inner volume. The positioning member includes a vacuum port disposed and configured to be aligned with a vacuum source to withdraw air from the inner volume of the sample bag.

Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis

Various embodiments are described herein for a system and method of integrated X-ray imaging and microscopic imaging of an imaging area having a sample on a sample stage. An X-ray apparatus may be disposed within the imaging area and be configured to acquire X-ray image data of at least a portion of the sample. A microscopic imaging apparatus may be disposed within the imaging area and be configured to acquire microscopic image data of the at least a portion of the sample. In some embodiments, a processing unit may then control the X-ray apparatus to acquire X-ray image data of the at least the portion of the sample, and generate one or more corresponding X-ray images; determine a region of interest (ROI) of the sample based on the one or more X-ray images; and control the microscopic imaging apparatus to obtain at least one microscopic image based on the ROI.

Method and system for combining microscopic imaging with X-Ray imaging

Various embodiments of systems and methods are described herein for obtaining wide field OCT images and other types of image data from at least one portion of a sample. Various embodiments of systems, and methods are described herein for assessing a degree of differentiation for a second region of an OCT image of a tissue sample with respect to another first. Various embodiments of a sample container are also described herein for containing a tissue sample and maintaining the tissue sample in a defined orientation during imaging or handling.

System and method for tissue differentiation in imaging

System and method for generating a wide-field OCT image of a portion of a sample

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Toronto, Canada

David Rempel