Gyrus Acmi, Inc.

Incline Therapeutics, Inc.

Koninklijke Philips Corporation N.V.

Alza Corporation

Insulet Corporation

David R Seward

Clifton A Alferness

Adam Lee Smith

Gina M Muia-Longman

Clinton Lee Finger

Zita S Netzel

Steven P Cardinali

Kevin Arnold Miller

Richard K Tanaka

Paul G Hayter

Bradley E White

John Timothy Lemke

Brian W Read

Corinna X Chen

Michael Palmisano

Matthew Alles

Robert Sanzone

Mary Friedl

Eric Healy

Tony Guard

Ayden Henson

Josh Haldeman

Jeffrey Barnes

David Desmarais

Derek Rund

Michael Nelson

Blake R Stancik

Donald Charles Baumgarten

David Andrew Desmarais

Amanda Kay Woodcock

Thomas Hall Ruscher

Chenhao Fu

Paul T Hinrichs

John Lemke

Ilia Timonin

Paul Hayter

Automated drug delivery device

A directed jet mouthpiece () comprises at least one mouthpiece trough () configured to fit over a front portion of a dental arch of a user's teeth. The at least one mouthpiece trough includes a buccal-side vertical member (), a lingual-side vertical member () and an occlusal-side horizontal member () extending in between. The at least one mouthpiece trough further includes at least one fluidics inlet (), a plurality of jet orifices () on both buccal- and lingual-side vertical members, and at least one fluidics path () disposed between the fluidics inlet and jet orifices. A plurality of directed jet orifices () is disposed in end regions () of the at least one mouthpiece trough. The at least one fluidics path () is further disposed between the fluidics inlet and plurality of directed jet orifices. The plurality of directed jet orifices () direct fluid jets rearward towards a remainder of teeth in a user's mouth beyond the end regions () of the at least one mouthpiece trough.

Mouthpiece with directed jets

Disclosed embodiments include apparatuses, systems, and methods for facilitating surgical anastomosis between bodily passages. In an illustrative embodiment, an eversion mechanism is configured to partially evert a distal portion of an opening of a receiving passage and further configured to leave a proximal portion of the opening of the receiving passage in a non-everted position. A donor support mechanism is configured to partially evert a distal portion of an opening at an end of a donor passage and further configured to leave a first proximal portion of the end of the donor passage in a non-everted position. The donor support mechanism is further configured to form a passage juncture at the end of the donor passage and the opening of the receiving passage. A suturing mechanism is configured to motivate a filament through a generally helical path around the passage juncture to suture the donor passage to the receiving passage.

Partial eversion anastomosis juncture formation and suturing

Disclosed embodiments include apparatuses, systems, and methods for driving a needle to facilitate suturing, such as may be performed in a surgical anastomosis procedure. In an illustrative embodiment, an apparatus includes a frame. First and second rollers are rotatably mounted parallel with each other in the frame and are configured to engage therebetween a shaft of a needle formed in a helical shape. The first and second rollers are configured to counter-rotate. The needle is revolvable eccentrically around the first roller responsive to counter-rotation of the first and second rollers. A drive mechanism is secured to the frame and is configured to move the frame.

Suturing apparatus and method

Mouthpiece with directed fluid jets

Disclosed embodiments include apparatuses, systems, and methods for facilitating surgical anastomosis. In an illustrative embodiment, an apparatus includes a first connector configured to engage an opening of a donor passage. A second connector is configured to engage an opening in a receiving passage. A separator is configured to support the first connector and the second connector and to fix relative positions of the end of the donor passage to edges of the opening in a receiving passage across a gap. The separator is configured to maintain the gap between the first connector and the second connector while multiple loops of a suture are passed through the edge of the opening in the donor passage and the edges of the opening in the receiving passage. The first connector, the second connector, and the separator are further configured to be removed from between adjacent loops of the multiple loops of the suture.

Removable anastomosis suturing support

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.

Method of storing an electrotransport drug delivery device

Iontophoretic drug delivery device

Two-part electrotransport device

Growing community of inventors

Seattle, WA, United States of America

David R Seward