Geno LLC

Vero Biotech Inc.

David R Rounbehler

David H Fine

Gregory Vasquez

Stephen J MacDonald

Jonathan L Rolfe

David B Wheeler

George Jarvis

Brian Johnson

A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

Conversion of nitrogen dioxide (NO) to nitric oxide (NO)

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Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)

Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.

Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.

Method and apparatus for nitric oxide generation

Nitric oxide delivery system

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Las Cruces, NM, United States of America

David R Rounbehler