Curium US LLC

David Pipes

Mark Owens

Lauren Radford

Craig Brunkhorst

Brian Regna

Shaun Loveless

Allan Casciola

William Uhland

Melissa Perrigo

Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.

Purification process for the preparation of non-carrier added copper-64

The present disclosure is directed compositions and formulations comprising high levels of copper-64, and process for preparing said compositions and formulations. The present disclosure also relates to methods of administering copper-64 compositions to a patient in need thereof.

Copper-64 compositions and formulations

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St. Louis, MO, United States of America

David Pipes