University of Massachusetts

Harvard College

The General Hospital Corporation

David Paydarfar

Hani Sallum

Riccardo Barbieri

James Niemi

Amanda Wozniak

Premananda Pai Indic

John Paul Osborne

Joshua Chang

Ruby Kandah

Elisabeth Bloch-Salisbury

Hani M Sallum

A system is described that observes a signal from a subject of interest, converts the signal to an electrical representation, uses the electrical representation to compute a synthetic control signal, and applies the synthetic control signal to control some aspect of operation of the subject. The procedure used to generate the synthetic control signal involves subjecting the electrical representation of the observed signal to random noise, allowing the extrema of the electrical representation to move, and obtaining a converged solution as the synthetic control signal.

Application of the extrema distortion method to optimize control signals

Systems and methods are disclosed to monitor physiological for the occurrence of life threatening events and to apply stimulation to prevent the occurrence of said life-threatening events. Systems and methods for applying the stimulation are also disclosed. These systems include applying the stimulation through via a mattress having a passive section and an active section, a plurality of focal stimulators, and/or an array to apply the stimulation are also disclosed. These devices include a mattress with an active region and a passive region, a stimulating array do deliver targeted stimulation, and a plurality of stimulators to apply focused stimulation.

Systems and methods for inhibiting apneic events

Systems and methods according to the present concepts reduce irritability in infants, such as infants suffering from neonatal abstinence syndrome (NAS) or colic. According to one embodiment, a method for reducing irritability in an infant includes determining one or more physiological measurements from an infant. The one or more physiological measurements relate to a state of irritability in the infant. The method also includes determining the state of irritability based on the one or more physiological measurements and applying a stochastic stimulation to the infant based on the state of irritability. The stochastic stimulation may be applied via a mattress. The stochastic stimulation may be vibro-tactile or subsensory.

Methods and systems for reducing irritability in infants

Growing community of inventors

Newton, MA, United States of America

David Paydarfar