The General Hospital Corporation

Children's Medical Center Corporation

E Ink Corporation

Optikos Corporation

David Paul Biss

Stephen D Fantone

Charles P Lin

Clemens Alt

Alicia L Carlson

Costas M Pitsillides

Stephen J Telfer

Richard J Paolini, Jr

Jeffrey Cerier

Sunil Krishna Sainis

Dirk Hertel

Benjamin Harris Paletsky

Daniel Orband

Anthony Maiorano

Brian E MacMillin

Chungiang Li

Chunqiang Li

Benjamin D Masella

An optical bulb for a medical device includes first and second bodies. The first body has a substantially hemispherical distal side. The second body extends from the first body and includes a mechanical connection point at or near the proximal side of the second body. An instrument channel extends through the optical bulb from the proximal side of the second body to the distal side of the first body. An imaging channel extends an aperture defined in the proximal side of the second body and terminates between the proximal and substantially hemispherical distal sides of the first body. The distal end of the imaging channel is substantially hemispherical. The first body is configured and arranged to provide a substantially uniform image path within a field of view of a camera disposed in the imaging channel.

Optical bulb for surgical instrument port

A display device () comprises a reflective display () arranged to render a first image viewable through a viewing surface and a projection means (-) arranged to render a second image viewable in reflection on the viewing surface, the reflective display () and the projection means (-) being mounted on a common frame.

Illumination systems for reflective displays

The present invention generally provides methods and systems for performing in vivo flow cytometry by using blood vessels as flow chambers through which flowing cells can be monitored in a live subject in vivo without the need for withdrawing a blood sample. In some embodiments, one or more blood vessels are illuminated with radiation so as to cause a multi-photon excitation of an exogenous fluorophore that was previously introduced into the subject to label one or more cell types of interest. In some other embodiments, rather than utilizing an exogenous fluorophore, endogenous (intrinsic) cellular fluorescence can be employed for in vivo flow cytometry. The emission of fluorescence radiation from such fluorophores in response to the excitation can be detected and analyzed to obtain information regarding a cell type of interest.

In vivo flow cytometry based on cellular autofluorescence

Apparatus for evaluating optical components and systems that uses a precision compact mirror support structure to present to an optical system or electro-optical system (e.g., a camera) multiple images of at least one optical evaluation target over a wide field to allow assessment of the performance or alignment of the optical or electro-optical system over its intended field of use. The mirror support structure generates multiple images of an optical evaluation target by providing multiple folded optical paths between the target and the desired field locations of the test optic. The mirrors employed may either be parallel or at angles with respect to one another.

Compact system for presenting wide field object target to test optic or system

Growing community of inventors

Brighton, MA, United States of America

David Paul Biss