Pfizer Corporation

David P Thompson

Patrick Robert Verhoest

Adam Matthew Gilbert

Rayomand Jal Unwalla

Edmund Lee Ellsworth

James Thomas Anderson

Anthony P Ricketts

Eugene Lvovich Piatnitski Chekler

Bruce Kipp Erickson

Eugene Lvovich Chekler

The present invention relates to a compound of Formula 1, 2 or 3: wherein A is N or &#x2014;CR&#x2014;, where Ris hydrogen, C-Clinear or branched chain alkyl, etc., Z is &#x2014;CR&#x2014;, or, &#x2014;N&#x2014;, where Ris hydrogen, C-Clinear or branched chain alkyl, etc.; Ris hydrogen, C-Clinear or branched chain alkyl, etc.; Rare independently hydrogen or C-Clinear or branched chain alkyl; Rand Rare independently hydrogen, C-Clinear or branched chain alkyl, etc.; Rand Rare independently hydrogen or C-Clinear or branched chain alkyl, etc.; Ris hydrogen, C-Clinear or branched chain alkyl, etc.; Rand Rare independently hydrogen or C-Clinear or branched chain alkyl, etc.; Q is &#x2014;CO&#x2014;, &#x2014;(CH)&#x2014;, &#x2014;(CHR)&#x2014;, or &#x2014;(CRR)&#x2014;, where Rand Rare independently C-Clinear or branched chain alkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl; where q is 0, 1, 2, or 3; and, where n is 0, 1, 2, 3, 4 or 5; or, a pharmaceutically acceptable salt thereof, to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly, those affected or mediated by the androgen receptor.

Selective androgen receptor modulators

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Battle Creek, MI, United States of America

David P Thompson