The Nutrasweet Company

Monsanto Company

Nsc Technologies

David P Pantaleone

Indra Prakash

David J Ager

Ronald E Barnett

Shyhyuan Liao

Ian G Fotheringham

Jennifer L Ton

Roxane Dikeman

Shyh-Yuan Liao

John Gill

Jeanine R Kittleson

The regioselective and chemoselective hydrolysis of an .alpha.-ester group of an amino acid diester using pig liver esterase enzyme (PLE) is disclosed. The amino acid diesters may be either N-protected or unprotected and the diester groups may be the same or different. In particular, the preparation of a number of .gamma.-ester glutamates and .beta.-ester aspartates are provided.

Regioselective .alpha.-hydrolysis of amino acid diesters using pig liver

A process and composition for preparing D-aspartic acid and .beta.-alanine from D,L-aspartic acid, wherein a solution of D,L-aspartic acid or a salt thereof is contacted with a composition having an L-aspartate-.alpha.-decarboxylase activity of greater than 100 .mu.mol L-aspartate used per hour per gram of cells, under appropriate conditions to produce D-aspartic acid and .beta.-alanine.

Process and composition for preparing D-aspartic acid

A novel method for the production of natural aromatic ester compounds such as methyl anthranilate, ethyl anthranilate butyl anthranilate methyl cinnamate and methyl salicylate comprises the esterification of their corresponding acids using microbially derived enzymes in the presence of a C.sub.1 -C.sub.4 alcohol such as methanol, ethanol or butanol. A biphasic reaction medium may optionally be utilized to generate maximum yields through the addition of a non-polar organic solvent such as hexane, ethyl acetate, heptane and the like.

Process for the synthesis natural aromatics

A modified hemicellulose A, hemicellulose B, modified hemicellulose A, modified hemicellulose B, or mixtures thereof are employed as water soluble bulking agents to replace the functional properties of carbohydrates or fats.

Water soluble bulking agents

Growing community of inventors

Buffalo Grove, IL, United States of America

David P Pantaleone