Becton Dickinson and Company Limited

David P Hopkins

Mohammad A Khan

Azhar J Khan

This invention relates to the use of vitamin E or its derivative, such as vitamin E acetate, with a silicone lubricant for use on a medical device. The vitamin E prevents degradation of the silicone lubricant when the medical device is irradiated for sterilization.

Radiation compatible lubricant for medical devices

This invention relates to a new water soluble lubricant for a medical device, such as a catheter and an introducer needle. The lubricant is a silicone surfactant which is non-ionic and which is a good lubricating fluid. Preferably the silicone surfactant that is used is a block copolymer polyalkylene oxide-modified polydimethylsiloxane. Water is used as the solvent for this lubricant. The lubrication solution includes a solution stabilizer to clarify the solution and antimicrobial agents to inhibit microbial growth in the water solution or on the coated product. Vitamin E or its derivatives may also be used in the lubrication solution. When the lubrication solution is used to lubricate Teflon products, a small amount of a low molecular weight alcohol is added to the lubrication solution to increase wettability.

Waterborne lubricant for teflon products

The two part tipping lubricant of this invention comprises water as the solvent. The lubricant is a silicone surfactant, which is non-ionic and which is a good lubricating fluid. No separate surfactant or lubricant is needed. The lubricant solution into which the catheter is dipped may also include low percentages of a solution stabilizer and an antimicrobial agent to clarify the solution and to inhibit microbial growth in the water solution. Vitamin E or its derivative may also be used in the lubrication solution to prevent degradation of the solution.

Water based lubricant solution

This invention relates to a new water soluble lubricant for a medical device, such as a catheter and an introducer needle. The lubricant is a silicone surfactant, which is non-ionic and which is a good lubricating fluid. Preferably the silicone surfactant that is used is a block copolymer polyalkylene oxide-modified polydimethylsiloxane. The lubrication solution includes a solution stabilizer to clarify the solution and antimicrobial agents to inhibit microbial growth in the water solution or on the coated product. Vitamin E or its derivatives may also be used in the lubrication solution.

Water soluble lubricant for medical devices

This invention relates to a process of making a shaped tip on a catheter. In this process, a lubricant solution is placed on a catheter, the catheter is placed on a mandrel, the catheter is heated, and the mandrel is engaged with a die to form a shaped tip on the catheter. The tipping lubricant of this invention comprises water as the solvent. The lubricant is a silicone surfactant, which is non-ionic and which is a good lubricating fluid. The lubricant solution into which the catheter is dipped includes low percentages of a solution stabilizer and an antimicrobial agent to clarify the solution and to inhibit microbial growth in the water solution. Vitamin E or its derivative may also be used in the lubrication solution.

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Salt Lake City, UT, United States of America

David P Hopkins