E.i. Dupont De Nemours and Company

David P Beach-Coffin

Donna Lynn Visioli

Clare A Stewart

Robert C Di Luccio

Linda R Bateman

Method of making tablets for active ingredient delivery by compressing a mixture of active ingredient and granular, high viscosity, fully hydrolyzed polyvinyl alcohol or copolymer of vinyl alcohol with methyl acrylate or methyl methacrylate. By use of a crystalline, heat treated polymer, a tablet providing quick active ingredient release is obtained. By using an amorphous, non-heat treated polymer a tablet providing prolonged active ingredient release is obtained. By using blends of crystalline and amorphous polymers, tablets having a range of active ingredient release characteristics can be obtained. The granular, high viscosity, fully hydrolyzed polymers provide flowability, compressibility and processing versatility advantages over conventional tablet binders.

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Lindenhurst, NY, United States of America

David P Beach-Coffin