Pfizer Corporation

Pfizer Products Inc.

David Morris Gethin

Denis Billen

Kim Thomas Hall

Nathan Anthony Logan Chubb

Lee Richard Roberts

Nigel Derek Arthur Walshe

Stephen Paul Gibson

Douglas James Critcher

Ivan Tommasini

Richard Edward Armer

Jessica Boyle

Graham Michael Kyne

Christopher J Dutton

Julian Duncan Smith

Nathan Anthony Chubb

Ashley Edward Fenwick

Kimberley Verrier

Nigel Derek Walshe

Catherine Frances Mccusker

This invention relates to a combination product comprising a compound of formula I wherein X, R, R, R, R, R, R, Rand Rare as described herein, and one or more further biologically active compounds as described herein, particularly anti-parasitic agents.

Substituted arylpyrazoles

This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

This invention relates to a combination product comprising a range of 1-aryl-4 -cyclopropylpyrazoles in which there is at least one fluorine attached to the cyclopropyl ring, and one o more further therapeutic agents, particularly anti-parasitic agents.

This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which there is at least one fluorine attached to the cyclopropyl ring, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

There is provided a compound of formula I,wherein R, R, Rand Y have meanings given in the description, which are useful in the prophylaxis and in the treatment of pruritus.

Compounds useful in therapy

4-arylpiperidine derivatives for the treatment of pruritus

Novel compounds having general formula (I), and pharmaceutically and veterinarily acceptable salts thereof wherein R , R , R , W, Y , Y , X, n and y are as defined above and processes for their preparation and intermediate compounds prepared therein. The novel compounds are useful for having utility in the treatment of pruritic dermatoses including allergic dermatitis and atopy in animals and humans.

4-phenylpiperidines for the treatment of pruritic dermatoses

Growing community of inventors

Sandwich, United Kingdom

David Morris Gethin