Sanofi-a Ventis Deutschland Gmbh

Conopco, Inc.

Sanofi-aventis Detuschland Gmbh

David Moore

Malcolm Stanley Boyd

David Sanders

Simon Lewis Bilton

James Alexander Davies

Steven Wimpenny

Christopher Nigel Langley

Marc Holtwick

Joseph Butler

Ilona Eggert

Paul Richard Draper

Stephen Francis Gilmore

John David Cross

Christopher Clarkson Jones

Anthony Paul Morris

Daniel Thomas De Sausmarez Lintell

Christian Nessel

Barry Yates

Naceur Rekaya

Jeffrey Zajac

Christopher James Smith

Richard James Vincent Avery

Garen Kouyoumjian

Shane Alistair Day

Aled Meredydd James

Michael James David Heald

Ross MacArthur

David Martin Leak

Alasdair George Young

Graham Jay

Graham Paul Randall

James Mark Watson

Oliver Benjamin Brown

The present disclosure relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present disclosure.

Joining technology of a dispense interface

The invention relates to an apparatus comprising an electromechanical device, a control unit and a motion detector, wherein said electromechanical device is controllable by said control unit via a control signal, wherein said motion detector is configured such that said mechanical movement of said electromechanical device is determined and wherein said motion detector provides a motion detector signal. The invention also relates to a method for operating an electromechanical device. The technical problem of providing an apparatus with an electromechanical device, the reliability as well as the power consumption of which is improved, is solved in that the control unit is configured such that it can be influenced by the phase difference between the control signal and the motion detector signal. The technical problem is also solved by a method for operating an apparatus, in particular an apparatus according to the invention, comprising the steps of running an electromechanical device with a control signal, producing a motion detector signal from a mechanical movement of said electromechanical device and influencing said control signal in dependence of said phase difference between said control signal and said motion detector signal.

Apparatus comprising electromechanical device and motion detector and method for operating apparatus

Drug delivery device

The invention provides a container () for the packaging of a fluent product (P) which off-gases, the container comprising: a container body () for receiving and storing product and a removable lid () for closing the container body; in which the lid is provided with a venting assembly () extending into the container body; in which the venting assembly has a closed position which is effective to close the container body and a venting position permitting the venting of gas from the container body; whereby, when the container body is partially filled with a fluent product which off-gases, the venting assembly moves to the venting position in response to excessive pressure from accumulated gas, and reverts to the closed position upon release of the excessive pressure, thus effecting periodic venting of the container body; and whereby the spatial arrangement of the venting assembly within the container body provides for venting of the container body independently of the orientation of the container, while retaining the product within the container body. The container is especially suitable for the packaging of viscous or semisolid products which incorporate an oxidizing agent, such as creams or gels for the bleaching or coloring of hair.

Container

The invention is related to a dispense interface for a drug delivery device for delivering at least two drug agents, comprising at least two two-ended flow regulation structures and a confluence, wherein each flow regulation structure comprises a fluid inlet opening at a first end, wherein each flow regulation structure comprises a fluid outlet opening connected to the confluence at a second end of the respective flow regulation structure and wherein at least one of the two-ended flow regulation structures comprises a capillary fluid channel. The invention is further related to a drug delivery device for delivering at least two drug agents comprising a dispense interface of the aforementioned kind, to a method for delivering at least two drug agents through an injection means of a drug delivery device and to a method for manufacturing a dispense interface of the aforementioned kind.

Capillary channel structure for dispense interface

The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.

The invention relates to an apparatus, in particular for ejecting a fluid, having an electric motor (), the motor comprising at least one motor winding (-), having a control unit () for controlling the motor (), wherein the apparatus further comprises an electronic detection circuitry () configured to determine an electrical quantity, the electrical quantity being a function of the electric resistance (Rw) of the motor winding (-), and wherein the control unit () is configured to control the motor () as a function of the electrical quantity. The invention further relates to a method for controlling such an apparatus, comprising the steps of: determining an electrical quantity, the electrical quantity being a function of the electric resistance (Rw) of the motor winding (-); and controlling the motor () as a function of the electrical quantity.

Apparatus with motor winding resistance measurement and method for controlling such an apparatus

A dispense interface for use with a drug delivery device. The dispense interface comprises a main outer body and an inner body. The inner body may be configured for connection to a drug delivery device and defines a first reservoir and a second reservoir. A first piercing needle is in fluid communication with the first reservoir and positioned for piercing a first cartridge of a drug delivery device. A second piercing needle is provided and in fluid communication with the second reservoir and positioned for piercing a second cartridge contained with a drug delivery device. A manifold is positioned adjacent the inner body and comprises a fluid groove arrangement. A valve arrangement is positioned between the inner body and the manifold and controls fluid communication of a first fluid contained in the first cartridge and a second fluid contained in the second cartridge by way of the fluid groove arrangement to a holding chamber. The dispense interface may further comprise a lockout preventing dispense interface reuse.

Dispense interface for use with a drug delivery device for delivery of two or more drug agents

The invention faces the technical problem of providing a tight connection between a tube and an dispense interface, while at the same time the biocompatibility of the connection can be improved. The technical problem is solved by an apparatus comprising a tube configured to guide a medium and a dispense interface. The tube comprises a first opening and a second opening, while the dispense interface comprises a recess. The recess has a first opening and a second opening and the tube is at least in part inserted into the recess. The tube is permanently affixed to the dispense interface by a combination of an interference fit and an adhesive, such that the interference fit prevents the adhesive from contaminating the medium.

Connection for medical device

The invention is related to a manifold comprising at least two valve receptacles, further comprising a fluid groove arrangement comprising at least two fluid grooves, wherein a first fluid groove of the at least two fluid grooves has a starting point near a first valve receptacle of the at least two valve receptacles and an end point near a second valve receptacle of the at least two valve receptacles and wherein a second fluid groove of the at least two fluid grooves has a starting point near a second valve receptacle of the at least two valve receptacles. The invention is further related to an apparatus comprising a manifold of the aforementioned kind and further comprising an inner body of a dispense interface.

Z-shaped fluid channel arrangement

The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.

Lockout element for dispense interface

A medicated module () for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module () containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle (). The medicated module () does not require the user to manually engage a reservoir () containing the secondary medicament. Instead, a biasing member () automatically activates the reservoir () when the needle guard () is retracted. The needle guard () prevents accidental needle sticks before and after an injection, and locks after dose delivery.

Medicated module with automatic reservoir engagement

The invention faces the technical problem of reducing the uncertainty over exact doses ejected from a medical device and at the same time providing a homogeneous, but controlled mixture of at least two fluids while a simple production should be maintained. A medical device comprising a first valve, a second valve, a first pre-valve ullage, a second pre-valve ullage, a post-valve ullage with a first end and a second end and a needle is presented. The first pre-valve ullage is connected to the post-valve ullage by the first valve and the second pre-valve ullage is connected to the post-valve ullage by the second valve. A first fluid is guidable from the first pre-valve ullage to the post-valve ullage and a second fluid is guidable from the second pre-valve ullage to the post-valve ullage.

Valve arrangement for medical device

The invention is related to an apparatus comprising a dispense interface comprising a lockout element for use with a drug delivery device, the lockout element comprising at least one spring component removeably maintained in a respective first position such that when the dispense interface is first attached and then removed from said drug delivery device, each spring component moves into a respective second position, which respective second position is configured to prevent said dispense interface from being reattached to a drug delivery device.

Dispense interface with lockout element

A dispense interface for use with a drug delivery device with an inner body and with a lockout element. The lockout element is coupled to the inner body movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device. In the locked condition, the dispense interface is not-attachable to the drug delivery device. The lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device.

Growing community of inventors

Leicestershire, United Kingdom

David Moore