Eli Lilly and Company

Other

David Mendel

Michael Robert Wiley

Gerald Floyd Smith

John Joseph Masters

David Kent Herron

Ying Kwong Yee

Jeffry Bernard Franciskovich

Anne Louise Tebbe

Valentine Joseph Klimkowski

Jason Scott Sawyer

Douglas Wade Beight

Steven E Hall

James Howard Wikel

Robert T Shuman

Jennifer Marie Tinsley

Trelia Joyce Craft

Leonard Crayton Weir

Theodore Goodson, Jr

Guy Milot

Jeffrey Alan Kyle

Sajan Joseph

Angela Lynn Marquart

Marta Maria Pi&ntilde;eiro-N&uacute;&ntilde;ez

Andrew Michael Ratz

Leander Merritt

Philip Parker Waid

Carl Penman Denny

Timothy Paul Burkholder

James Robert Henry

Joshua Ryan Clayton

Johnathan Alexander McLean

Marta Maria Pi&ntilde;eiro-Nu&ntilde;ez

Theodore Goodson, Junior

Jon Kevin Reel

Leland O Weigel

Sushant Malhotra

David Michael Remick

Thomas Albert Engler

Yihong Li

Yan Hao

David Anthony Barda

Boyu Zhong

Marta Maria Pineiro-Nunez

Kelly Wayne Furness

Yvonne Yee Mai Yip

Clive Gideon Diefenbacher

Jared Harris Linebarger

Salvatore Donato Lepore

Brian Raymond Berridge

Charles Edward Ruegg

John Morris Sullivan

John Monte Knobeloch

Mark Edward Rempala

Zhao-Qing Wang

Marta Maria Pinelro-Núnez

Guy Milet

Theodore Goodson Jr

Jeffrey Bernard Franciskovich

Ankush Baburao Argade

Perry Clark Heath

Theodore Junior Goodson

Ankush B Rigel Pharmaceuticals Inc Argade

The present invention provides kinase inhibitors of Formula I. 

Purine derivatives as kinase inhibitors

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. An example of a compound of formula (I) is (a). 

Aromatic ether derivatives useful as thrombin inhibitors

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. 

Antithrombotic diamides

The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds. 

Imidazo[1,2-A]pyridine compounds as VEGF-R2 inhibitors

This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor (I). 

Antithrombotic ethers

This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor.

Antithrombotic aromatic ethers

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor. 

Substituted heterocyclic carboxamides with antithrombotic activity

This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Substituted carboxamides

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Substituted heterocyclic amides

Aromatic amides

Antithrombotic amides

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Indianapolis, IN, United States of America

David Mendel