Eyeon Particle Sciences LLC

Santen Pharmaceutical Co., Ltd.

Calm Water Therapeutics LLC

Other

Empire Technology Development LLC

Lumetrics, Inc.

Cataract Innovations LLC

Cateract Innovations LLC

Macusight, Inc.

David Maxwell Kleinman

Eugene Rex Cooper

Andrew L Loxley

Mark Mitchnick

Thierry Nivaggioli

Mary E Gerritsen

David A Weber

Christopher T Cotton

Trevor Moody

Sreenivasu Mudumba

Filipp V Ignatovich

Philippe J M Dor

Todd Blalock

Kenneth Eugene Perry, Jr

The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.

Bi-functional co-polymer use for ophthalmic and other topical and local applications

The invention contemplates a copolymer which is a graft or block copolymer useful to change the ocular surface temperature and other characteristics of biological or contact lens surfaces. Methods for use of these formulations and coatings to increase the temperature of the skin, mucous membranes, eye or eyelids will help treat many conditions including blepharitis and non-healing ulcers. Methods to decrease evaporation, improve wettability and stabilize the tear film, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to improve contact lens tolerability, are provided.

An apparatus to treat a cataract where the cataractous lens is pierced and the resulting opening is mechanically maintained using a lens system device such as a cylindrical lens, tubular lens, pinhole device, a stent or similar small diameter device, or where the device itself is the lens. The resulting passageway for visible light created in the cataractous lens allows light to better reach the retina, thus improving vision. This lens system device that can be placed into an in situ cataract provides for a much simpler surgical technique and reduces related pre and post operative procedures and potential complications. Intraocular lenses may also be used in concert with this invention. The apparatus and related methods can be applied to humans as well as animals.

Apparatus for the treatment of cataract

Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.

Formulations and methods for vascular permeability-related diseases or conditions

An intravitreous stent includes a multi-loop single wire having a proximal end; a distal end; at least a first loop defined by the proximal end and a first portion of the single wire; at least a second loop defined by the distal end and a second portion of the single wire; wherein the first portion is joined to the second portion via a reversing loop portion.

Intravitreous self adaptive stent

A portable hand-held camera for imaging the fundus of an eye, the camera comprising a housing comprising an internal cavity terminating at a forward housing end, a forward lens, and a light source configured to direct light from locations distributed around the perimeter of the forward lens forwardly out of the housing end. In other embodiment, a portable hand-held camera for imaging the fundus of an eye includes optics configured to focus light reflected back from the fundus onto an image receptor, with the optics being capable of varying the field of view among differing portions of the fundus. Methods to ensure unique image identification and storage are described.

Portable fundus camera

Bi-functional co-polymer use for opthalmic and other topical and local applications

A method and related apparatus to treat a cataract where the cataractous lens is pierced and the resulting opening is mechanically maintained using a lens system device such as a pinhole device, expandable tubular lens, a stent or similar small diameter device, some of which are capable of supporting a secondary intraocular lens. The resulting passageway or lumen created in the cataractous lens allows visible light to better reach the retina, thus improving vision. This lens system device that can be placed into an in situ cataract provides for a much simpler surgical technique and reduces related pre and post operative procedures and potential complications. Intraocular lenses may also be used in concert with this invention. The apparatus and technique can be applied to humans as well as animals.

Method for the treatment of cataract

Growing community of inventors

Rochester, NY, United States of America

David Maxwell Kleinman