Sanofi-A Ventis Deutschland Gmbh

Smiths Medical Asd, Inc.

David Martin Leak

Malcolm Stanley Boyd

Daniel Thomas De Sausmarez Lintell

Christopher James Smith

Carmen Patricia Keating

Elizabeth Anne Marshall

David Sanders

Robert F Veasey

Christopher Clarkson Jones

Steven Wimpenny

Shane Alistair Day

Barry Yates

Aidan Michael O'Hare

Joseph Butler

David Aubrey Plumptre

Simon Lewis Bilton

Elliot L Ortiz

David Moore

Marc Holtwick

Michael James David Heald

Michael James Heald

Daniel David Higgins

Zdenek Cerman

Steven Albert Cote

Graham Jay

Alysa Lauren Granata

Jay Graham

Shiva Prakash Moosai

Ross Douglas Laurie MacArthur

Christopher Smith Smith

Ross Douglas Laurie Macarthur

Elliot Lucas Ortiz

A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.

Drug delivery device and method of operation

Drug delivery device and electro-mechanical injection device

Drug delivery device including motion detection system

Device and method for delivery of two or more drug agents

A dose setting mechanism for a drug delivery device. The mechanism may comprise a drug delivery device housing. A dose dial component is positioned in the housing and rotatable during dose setting and dose delivery. A split threaded insert is in threaded engagement with the dose dial component. The insert can transform from a first configuration to a second configuration when the dose dial component is rotated. In one dose setting mechanism arrangement, the first configuration may comprise a first open configuration and the second configuration may comprise a second closed configuration.

Dose setting mechanism and method of setting a dose

A dose setting mechanism for a drug delivery device is provided comprising a dose setting member and a further element. Maximum dose stop features are provided on a housing and on the further element.

Injection device with dose setting mechanism having maximum dose stop

The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a drug delivery device housing, a dose dial sleeve positioned at least partly in the housing and being rotatable during dose setting and dose delivery, a clutch rotatable during dose setting and non-rotatable during dose delivery, and a clutch nut, that is threadedly engaged with the clutch and is splined to the housing to prevent rotation of the clutch nut.

Dose setting mechanism and method of using same

Guidewire introducer

An injection system for co-delivery of two medicaments () having a drug delivery device () containing a primary reservoir () containing a first medicament () and having a secondary reservoir () containing a second medicament () where the drug delivery device () has only one dose setter () for the primary reservoir () and that automatically determines the dose of the second medicament (). Both medicaments () are delivered through a single dispense interface ().

Delivery of two or more medicaments through a single dose selection and dispense interface

A dose setting mechanism comprises a drug delivery device housing and a dual state track provided within the housing that is axially and rotationally fixed with respect to the housing. A dose dial component is positioned in the housing and rotatable during dose setting and dose delivery. A clutch is rotatable during dose setting and non-rotatable during dose delivery. A clutch plate is rotationally fixed relative to the housing; and a clutch blocker is in threaded engagement with the clutch plate and has a radial key engaged with the dual state track. The mechanism may comprise a biasing member positioned between the clutch blocker and clutch plate.

A drug delivery device having a spring element that provides dispense assistance. The drug delivery device includes a variable dose setting mechanism, a fixed dose setting mechanism, and a mechanical coupling having a spring element. The variable dose setting mechanism is operably coupled to a first reservoir holding a first medicament, and the variable dose setting mechanism comprises a dose setter. The fixed dose setting mechanism is operably coupled to a second reservoir holding a second medicament. The mechanical coupling operably couples the variable dose setting mechanism and the fixed dose setting mechanism. Further, the variable dose setting mechanism is configured to set a variable dose of the first medicament upon activation of the dose setter, and the fixed dose setting mechanism is configured to set a fixed dose of the second medicament during variable dose setting. Still further, the spring element is configured to store energy during dose setting and to transfer stored energy to the fixed dose setting mechanism to assist with dispense of the fixed dose.

Drug delivery device having a spring element

A drug delivery device having a trigger biasing member that provides dispense assistance. The drug delivery device includes a variable dose setting mechanism that is operably coupled to a primary reservoir holding a first medicament. The drug delivery device also includes a fixed dose setting mechanism that is operably coupled to a secondary reservoir holding a second medicament. The fixed dose setting mechanism comprises a trigger biasing member or spring. In addition, the drug delivery device includes a mechanical coupling that operably couples the variable dose setting mechanism and the fixed dose setting mechanism. During dose setting, activation of a single dose setter sets a variable dose of the first medicament. Setting of a minimum dose of the first medicament causes a fixed dose of the second medicament to be automatically set, and, during dispense, the trigger spring at least assists with the dispense of the fixed dose of the second medicament.

Drug delivery device having a trigger

A drug delivery device for co-delivery of two medicaments. The drug delivery device has a dose setter, a first dose dial component, a second dose dial component, and a collar. The first dose dial component is configured to select a first dose of a first medicament, and the first dose dial component is operably connected to the dose setter. The second dose dial component is configured to select a second dose of a second medicament. In addition, the first dose dial component and the second dose dial component are connected to the collar. The collar is configured to be moved in a proximal direction by actuation of the dose setter. Further, when the collar is moved in a proximal direction, the first dose dial component and the second dose dial component are configured to move proximally to set a dose 'A' for the first medicament with the first dose dial component and set a dose 'B' for the second medicament with the second dose dial component.

Drug delivery device having linked dose dial components

Growing community of inventors

Lake Hopatcong, NJ, United States of America

David Martin Leak