Edwards Lifesciences Corporation

Biointerventional Corporation

Edwards Lifesciences Ag

Other

Heartport, Inc.

Salix Pharmaceuticals, Inc.

Cardiva Medical, Inc.

Centurion Medical Products Corporation

Lifescan Corporation

IP Reservoir, LLC

Exegy Incorporated

Safdi, Alan

David Mark Taylor

Eric Robert Dixon

Sergio Delgado

Robert R Bowes

Alexander J Siegel

Matthew T Winston

Asher L Metchik

Philippe Marchand

David J Evans

Ronaldo C Cayabyab

Gregory Scott Tyler, Ii

Christopher Chia

Robert Milich

Lauren R Freschauf

Alexander H Cooper

Thanh Huy Le

Tri D Tran

Sam Sok

Gordon Howard Epstein

Brian Benjamin Martin

Christopher J Olson

Larry L Wood

Todd E Lempert

Randall T Lashinski

Henry Bourang

Yoon Hee Kwon

Arnold Cruz Tuason

Devin H Marr

Mark Chau

Wesley D Sterman

Darshin S Patel

A Adam Sharkawy

Bao Khuu

Pinaki Ray

Mario M Iobbi

Amanda Kristine Anderson White

Antonio O Vidal

Robert Royal Bowes

Emil Karapetian

David Leigh Hauser

Thomas V Doherty

Scott Parsons

Sean Chow

Matthew J Birdsall

Michael R Bialas

Jan R Lau

Cristobal R Hernandez

Rajesh A Khanna

Michael J Popp

Richard M Romley

Pui Tong Ho

Zachary R Kowalski

Art Z Kwan

Hanson S Gifford, Iii

Michi E Garrison

Richard S Kusleika

Daniel C Rosenman

Jan Komtebedde

Grant Matthew Stearns

Jeremy Walter Whatley

Rajesh Khanna

Kwame Gyang

Richard Bradley

Kevin Vincent Grimes

Victoria Cheng-Tan Wu

Tam Van Nguyen

Michael Dewulf

Robert Bowes

Larry Wood

Stanton J Rowe

Boaz Manash

Zia Yassinzadeh

Ofir Witzman

Eric D Bailey

Michael Robert Forman

Gerard Von Hoffmann

Yoav Rozen

Alex Philip McCann

Glenn Foy

Philip P Corso, Jr

Mark H Olson

Amanda K Anderson

Rachel Liat David Foreman

Rachel Ann Cooney

Mario M Gabriel Iobbi

Greg Matian

Grant Jason Gangeness

Carrie Arndt

Murphy Freelen

Jason Nierescher

Alan Safdi

Dave J Evans

Rhayoung Kwon

Mario Iobbi

Ulrich Kraft

Gregory Scott Ii Tyler

The present disclosure provides a stabilizing system for a medical device. The stabilizing system includes a table and a stabilizing unit. The table includes a table having a base member and an upper member. The upper member is removably mounted on top of an upper portion of the base member. The upper member includes an inverted T-shaped slot. The stabilizing unit includes a base portion and a support member. The base portion has side rails. The support member is disposed on the base portion. The support member is configured to receive and support a catheter assembly comprising a catheter and a catheter handle. The stabilizing unit is mounted to the upper member of the table by sliding the side rails into the inverted T-shaped slot.

Medical device stabilizing apparatus and method of use

Embodiments of the present disclosure include an implantable assembly for a native heart valve that includes a prosthetic heart valve and a braided support structure. The prosthetic valve includes a frame and prosthetic leaflets. The braided support structure has an inner braided layer and an outer braided layer. The outer braided layer is disposed over the inner braided layer. The outer braided layer is less porous to blood than the inner braided layer. The braided support structure defines a plurality of arms that are angularly spaced around the prosthetic heart valve such that each arm extends radially outwardly from the prosthetic heart valve. Other embodiments are also described.

Prosthetic heart valve docking assembly

A stabilizing unit for a medical device includes a base member, a housing, a stabilizing fork, one or more springs, and a retaining arm. The housing has a lower housing portion and an upper housing portion connected to the lower housing portion. The lower housing portion is disposed in a laterally extending slot of the base member. The stabilizing fork is disposed in the upper housing portion. The one or more springs extend into the stabilizing fork. The retaining arm is slidably coupled to the upper housing portion. The retaining arm retains the stabilizing fork in the upper housing portion.

A method for deploying an expandable prosthetic heart valve in a patient includes introducing a guidewire into a patient and advancing the guidewire through a vasculature of a patient to a deployment site. A distal end portion of a delivery apparatus and the prosthetic heart valve mounted in a radially compressed configuration along the distal end portion are advanced over the guidewire. The prosthetic heart valve is positioned at the deployment site. A screw mechanism is rotated, which exerts an axially directed onto the prosthetic heart valve, causing the prosthetic heart valve to radially expand from the radially compressed configuration to a radially expanded configuration.

Method for deploying a prosthetic heart valve

A method of implanting a balloon expandable prosthetic valve within a native aortic valve includes introducing a delivery system into a femoral artery of a patient, the delivery system comprising an outer sleeve and a shaft extending through a lumen of the outer sleeve. A distal end portion of the shaft is positioned distal to a distal end of a steerable distal end portion of the outer sleeve. A prosthetic valve is crimped over a balloon disposed along the distal end portion of the shaft. The delivery system further comprises a first radiopaque marker inside the balloon and positioned adjacent a proximal end of the prosthetic valve and a second radiopaque marker inside the balloon and positioned adjacent a distal end of the prosthetic valve. The method also includes identifying a location of the prosthetic valve by monitoring the first and second radiopaque markers inside the balloon under fluoroscopy.

Method for delivering a prosthetic heart valve

Certain aspects of the disclosure concern a device for repairing or replacing a native heart valve. The device can include a frame including a first set of struts intersecting with a second set of struts at a plurality of strut connection points. The frame can be radially expandable from a radially collapsed state to a radially expanded state. The device can include at least one expansion feature including a screw head and a screw shaft connected to the screw head. The screw shaft can extend through a first strut connection point and a second strut connection point. The device can further include a plurality of penetrating members extending from a first end of the frame. Rotating the screw shaft in a first direction can radially expand the frame from the radially collapsed state to the radially expanded state.

Cardiac valve repair devices configured for percutaneous delivery

An device for treating a native valve includes a sealing element and an anchoring element. The sealing element is made from a braided mesh material. The sealing element is dimensioned to be deployed in an annulus of a native valve of a heart at a position between native valve leaflets to contact the native valve leaflets during ventricular systole to create a seal to prevent regurgitation of blood from the left ventricle to the left atrium. The sealing element is configured to both be radially expanded and radially reduced while at the position between the native valve leaflets. The anchoring element is adapted for deployment in the heart, the anchoring element coupled to the sealing element and configured to support the sealing element at the desired position between native valve leaflets.

Heart valve sealing devices and delivery devices therefor

A valve repair system for repairing a native valve of a patient includes a catheter and a valve repair device. The valve repair device is disposed in the catheter. The valve repair device comprises a compressible spacer and a pair of paddles. The pair of paddles are moveable between an open position and a closed position. The valve repair device can transition to a compressed configuration with the compressible spacer between the pair of paddles in the closed position.

Assemblies and delivery apparatus for delivering a medical device into a patient's vasculature are disclosed. In some examples, an assembly includes a delivery apparatus and a radially compressible and expandable prosthetic heart valve. The delivery apparatus includes a handle, a first shaft and a second shaft extending from the handle, and a locking mechanism to prevent axial movement of the second shaft relative to first shaft. The second shaft extends coaxially through the first shaft and includes, at a distal end portion thereof, a balloon, one or more radiopaque markers, and the prosthetic valve radially compressed over the balloon. A flared end piece extending from the first shaft covers a proximal portion of the balloon during advancing of the delivery apparatus through a patient's vasculature. The first shaft is retractable relative to the second shaft to expose the balloon from the flared end piece.

Delivery apparatus for prosthetic heart valve

In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube and a nose cone cap. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. The nose cone cap and the storage tube have mating first and second locking member that can be coupled to selectively secure the nose cone cap to the storage tube.

Storage assembly for prosthetic valve

A valve repair delivery handle includes a housing, an actuation control mechanism, and a clasp control mechanism. The actuation control mechanism includes a knob and an actuation tube. The knob is rotatably coupled to the housing. The actuation tube is coupled to the knob such that rotation of the knob in a first direction moves the actuation tube distally relative to the housing and rotation of the knob in a second direction moves the actuation tube proximally relative to the housing. The clasp control mechanism is coupled to the housing.

Valve repair delivery handle

In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be configured to extend radially outwardly as the spacer body extends away from the distal end toward the proximal end. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

A valve catheter is advanced through a patient's vasculature while a prosthetic heart valve is attached to flexible extensions along a distal end thereof. The valve catheter is advanced through a tubular sleeve for exposing the prosthetic heart valve and allowing the prosthetic heart valve to self-expand while the extensions remain attached to the prosthetic heart valve. A release mechanism on a handle portion is actuated for releasing the prosthetic heart valve from the extensions, thereby implanting the prosthetic heart in a native heart valve. If the operator is not satisfied with the initial expansion, the prosthetic heart valve may be reoriented before release from the extensions by retracting the prosthetic heart valve back into the tubular sleeve, adjusting the orientation of the prosthetic heart valve and then re-advancing the valve catheter from the tubular sleeve for allowing the prosthetic heart valve to re-self-expand at a more desirable location.

Method of implanting a heart valve

Embodiments of the present disclosure provide an introducer device and methods for introducing a medical device into a patient's vasculature. In one embodiment, a method of using an introducer device including a housing, a hemostatic seal mounted within the housing, and a tube extending into the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position, includes moving the tube to the distal position such that the distal end of the tube extends through the hemostatic seal. The method further includes inserting a distal end portion of the medical device through the tube and into the patient's vasculature without contacting the hemostatic seal.

Introducer device for medical procedures

A valve repair devices and systems for repairing a native valve of a patient include a spacer, a pair of paddles, and a pair of moveable clasp arms. The pair of moveable clasp arms are disposed between the pair of paddles and the spacer. The moveable clasp arms are configured to attach to leaflets of a heart valve. The spacer, the pair of paddles, and the moveable clasp arms are configured such that, when attached to the leaflets, the moveable clasp arms are located between the spacer and first portions of the leaflet, while second portions of the leaflet engage the spacer.

Growing community of inventors

Lake Forest, CA, United States of America

David Mark Taylor