California Institute of Technology

Centre National De La Recherche Scientifique

Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris

Inserm (institut National De La Sante Et De La Recherche Medicale)

David Maresca

Mikhail G Shapiro

Avinoam D Bar-Zion

Atousa Nourmahnad

Richard A Andersen

Mickaël Tanter

Daniel P Sawyer

Sumner L Norman

Vasileios Christopoulos

Charlie Demene

Methods and systems are provided for decoding movement intentions using functional ultrasound (fUS) imaging of the brain. In one example, decoding movement intentions include determining a memory phase of a cognitive state of the brain, the memory phase between a gaze fixation phase and movement execution phase, and determining one or more movement intentions including one or more of intended effector (e.g., hand, eye) and intended direction (e.g., right, left) according to a machine learning algorithm trained to classify one or more movement intentions simultaneously.

Decoding movement intention using ultrasound neuroimaging

The system and process of therapeutic and effective cavitation by using ultrasound to collapse gas vesicles as well as cavitate the bubbles produced from the collapsed gas vesicles. Therapeutic effect includes, but is not limited to lysing cells by cavitation. The cells expressing the gas vesicles can optionally be used as delivery cells to preform tasks such as transporting the gas vesicles into deep tissue areas, releasing compounds at the cavitation site, and more. The gas vesicles can optionally be modified to facilitate getting the bubbles near the cavitation targets by functionalizing the gas vesicles.

Compositions, methods and systems for gas vesicle based cavitation

Certain embodiments pertain to cross-amplitude modulation (xAM) ultrasound imaging methods and systems configured to excite a first subaperture of transducer elements to transmit a first ultrasound plane wave, excite a second subaperture of transducer elements to transmit a second ultrasound plane wave noncollinear to the first ultrasound plane wave, the second ultrasound plane wave axisymmetric to the first ultrasound plane wave about a bisector, and simultaneously excite both first and second subapertures to transmit first and second ultrasound plane waves to cause an acoustic pressure above a threshold along the bisector.

Cross amplitude modulation ultrasound pulse sequence

Growing community of inventors

Pasadena, CA, United States of America

David Maresca