Convergence Pharmaceuticals Limited

David MacPherson

David Witty

Gerard M P Giblin

Steven J Stanway

Michael John Williams

William F Kiesman

Tamera L Mack

Gerard Giblin

Donald Walker

Tamera Mack

The invention relates to a novel process for preparing &#x3b1;-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for preparing said intermediates.

Process for preparing alpha-carboxamide pyrrolidine derivatives

The invention relates to spiro deriviatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.

Pyrimidinyl-diazospiro compounds

The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.

The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.

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Cambridge, United Kingdom

David MacPherson