Imperial College of Science, Technology and Medicine

Micromass UK Limited

Imperial College Innovations Limited

David Macintyre

Steven Derek Pringle

Keith George Richardson

Emrys Jones

Michael Raymond Morris

James Ian Langridge

Tamás Karancsi

Dániel Szalay

Zoltán Takáts

Pamela Pruski

Lajos Gödörházy

Philip Bennett

Vasiliki Terzidou

Joanna Cook

Júlia Balog

Dániel Simon

Phillip Bennett

The present invention provides method for predicting risk of cervical shortening, methods for predicting risk of preterm labour (PTL), and methods for characterising a pregnant subject having a history of previous PTL, mid-trimester loss or cervical cone biopsy as being in need of surveillance and/or intervention to prevent preterm labour, comprising determining the expression level of one or more of the miRNA molecules identified in Table 1 or Table 2 extracted from a biological sample obtained from said subject and comparing to a control value. Biochips and kits for use in carrying out the methods of the invention are also provided.

Method for predicting cervical shortening and preterm birth

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London, United Kingdom

David Macintyre