Wyeth Pharmaceuticals, Inc.

Tmri, Ltd

Aberdeen University Research and Innovation

David Macaulay Reid

Jennifer Susan Gregory

Richard Malcom Aspden

Rebecca Jane Barr

Kanako Yoshidashire

Kanako Yoshida

Richard Malcolm Aspden

An apparatus and method for analyzing the morphometry of a human hip joint is provided. The apparatus includes image receiving means for receiving a digital image of a hip joint and image analysis means, including an Active Shape Model configured to identify a set of landmark points on the image, wherein the set of points includes points which correspond to features of the proximal femur and the region of the pelvis forming the acetabulum. The ASM is further configured to generate an image data-set from the co-ordinates of the landmark points; and data comparison means for comparing the image data-set with one or more comparative data-sets to obtain value(s) for one or more output modes which characterize the variation of the image data-set from the comparative data-set(s), to provide an indication of the presence and/or severity of osteoarthritis in the hip and/or the risk of the hip joint developing osteoarthritis.

Morphometry of the human hip joint and prediction of osteoarthritis

Apparatus and method for analyzing the morphometry of a human knee joint. The apparatus comprises:

Morphometry of the human knee joint and prediction for osteoarthritis

An apparatus is disclosed for predicting bone fracture risk in an osteoporotic patient. The apparatus comprises a Dual X-ray Absorptiometry scanner for scanning a body area of the patient and producing a Dual X-ray Absorptiometry image of the body area, and image analysis means for analyzing pre-determined aspects of the Dual X-ray Absorptiometry image. The apparatus further comprises data comparison means comprising a database of comparative data sets from Dual X-ray Absorptiometry images of control subjects to predict the risk of bone fracture in the patient. The image analysis means preferably analyses the shape of a body past using an Achieve Shape Model or analyses the texture of a body past using Fourier Transforms and Principal Component Analysis.

Apparatus for predicting bone fracture risk

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Aberdeen, United Kingdom

David Macaulay Reid