Bayer Corporation

Bayer Cropscience Gmbh

Bayer Aktiengesellschaft

Bayer Cropscience Ag

Miles Inc.

David M Mayes

Vidyanatha A Prasad

Klaus Stroech

Peter E Newallis

Hermann Seifert

Eric Rivadeneira

Vijay C Desai

Daniel M Wasleski

Joe J Hanson

Shekhar Kulkarni

Karl G Steinbeck

Gerd Grah

Shekhar V Kulkarni

The present invention provides a method of preparing 1-acetyl-1-chlorocyclopropane from 1,3 dichloro-2-pentanone by reaction with base in the presence of a phase transfer catalyst. The reaction may be run in the presence or absence of an organic solvent and in a continuous or batch process.

Method of preparing 1-acetyl-1-chlorocyclopropane

Processes for preparing &agr;-substituted benzylnitroguanidines include the steps of providing a reaction mixture comprising water, alcohol, an S-alkyl nitroisothiourea, and an &agr;-substituted benzylamine; heating the reaction mixture; steam distilling the alcohol from the reaction mixture; and isolating an &agr;-substituted benzylnitroguanidine from the remaining water layer.

Processes for the preparation of &agr;-substituted benzylnitroguanidines

The invention relates to process for the preparation of an O-alkyl, O-alkyl phosphorochloridothioate by 1) reacting A) a thiophosphoryl halide with B) an alcohol, in the presence of C) a tertiary amine acid acceptor and D) a solvent, and 2) reacting the resultant product with a second alcohol, different from the alcohol used in step 1). In the preferred embodiment, the intermediate product is not isolated before reaction with the second alcohol.

Process for preparing O-alkyl, O-alkylphosphorochloridothioates

Disclosed herein is an improved process for preparing methyl dithiocarbazinate by reacting carbon disulfide and hydrazine in an effective ratio to form hydrazinium dithiocarbazinate, followed by methylating the hydrazinium dithiocarbazinate with methyl bromide. The improvement resides in conducting the reaction of the carbon disulfide and hydrazine in the presence of a specified amount of a non-alcoholic solvent to reduce dithiocarbazinate buildup.

Process for reducing dithiocarbazinate buildup in the preparation of

Substituted 4-amino-1,2,4-triazine-5-ones are purified to remove unwanted N-isomers by maintaining the crude product at a temperature of from about 55.degree. C. to about 70.degree. C. in the presence of a hydroxide, preferably an alkali metal hydroxide for at least 0.5 hour.

Process for the purification of substituted 4-amino-1,2,4-triazine-5-ones

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Overland Park, KS, United States of America

David M Mayes