Centocor, Inc.

New York University

Janssen Biotech, Inc.

Applied Molecular Evolution

Other

Resource Fiber LLC

Centocor Ortho Biotech Inc.

The State University of New York

Global Bamboo Technologies, Inc.

Teragren LLC

Cna Development LLC

Centocor Research & Development, Inc.

Ortho Biotech Holding LLC

David M Knight

John Ghrayeb

David J Shealy

Jan T Vilcek

Scott A Siegel

Junming Le

Peter E Daddona

Jill M Giles-Komar

Bernard Scallon

David Peritt

George A Heavner

Raymond W Sweet

Vedrana Stojanovic-Susulic

Alain Philippe Vasserot

Sheng-Jiun Wu

David Matthew Marquis

Jing Yang

Bailin Liang

Eric Michael Smith

Debra Gardner

Michael W Lark

Yan Chen

Susan H Tam

Jinquan Luo

Leland Slaven, Jr

Xiao-Yu R Song

Xiao-yu R Song

Mohit Trikha

Barry S Coller

Thomas C Nesspor

Peter Dadonna

Chichi Huang

Randall J Brezski

Mary Ryan

Robert Jordan

Diane Petrone

Mark Hilary Cunningham

Juan C Almagro

Gopalan Raghunathan

John Wheeler

Jill Carton

Kristen Picha

Robert T Sarisky

Lani Rose San Mateo

Ping Tsui

Mark Tornetta

Karen Duffy

Jin Lu

Brian Whitaker

Roberta Lamb

Qiang Chen

Anuk Das

Shizhong Chen

Shanrong Zhao

Robert E Jordan

Mouhamadou L Mbow

Bernard Amegadzie

Jumming Le

Susan Tam

Yan Chan

Nicole Stowell

Yongjin Chen

Scott Seigal

Theresa J Goletz

Lei Shi

Lionella Borozdina-Birch

Ramachandra Reddy

Karen A Kutoloski

John Ghraveb

Carrie Lynne Wagner

James E Looney

Jr Slaven

Bernhard Scallon

Lani San Mateo

Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.

Anti-IL-6 antibody

The present technology relates generally to a platform and concrete composite slab system used as a building material. A platform, is formed from joined, substantially coplanar boards with connector plates partially embedded between the boards such that a portion of the connector plates extend above the platform's top surface. A reinforcing material (e.g., wire mesh and/or rebar) can be arranged on the prongs or other portion of the connector plates spaced above the platform and concrete is poured over the reinforcing material and allowed to cure, forming a reinforced concrete layer that encases the connector plates and reinforcing material. The connector plates act as standoffs and help to suspend the reinforcing material in the middle of the concrete layer to increase the strength of the reinforced concrete and to fixedly anchor and bind the concrete layer to the platform, so as to establish a composite action between the platform and the concrete.

Laminated bamboo platform and concrete composite slab system

Methods of suppressing rheumatoid arthritis using an anti-IL-6 antibody

A vegetable cane fiber ballistic impact panel and process of manufacturing the ballistic panel. The ballistic panel includes a plurality of vegetable cane fibers (e.g., bamboo fibers) impregnated with a polymer. The vegetable cane fibers are formed into mats of interconnected and entangled fibers and the polymer is formed into polymer films. The polymer films and mats are arranged into a layered assembly having an alternating arrangement and pressed together. The layered assembly is heated to soften the polymer and allow it to flow around the vegetable cane fibers to impregnate the vegetable cane fibers and then cooled. The vegetable cane fibers are generally uniformly distributed through the entire thickness of the panel and vegetable cane fibers originally formed within different mats are entangled with each other.

Bamboo and/or vegetable cane fiber ballistic impact panel and process

Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as systemic lupus erythematosus.

Method for treating lupus by administering an anti-IL-12 antibody

Systems, methods, and apparatus for conditioning bamboo or other types of vegetable cane are provided. In one aspect, the present technology provides a cane processing assembly for use with a substantially flattened sheet of bamboo culm or vegetable cane having a plurality of longitudinally oriented fiber bundles. The assembly comprises first and second conditioning rollers configured to apply pressure to the sheet that breaks at least some natural bonds connecting laterally adjacent fiber bundles in the sheet. The first and second conditioning rollers are adjustable relative to each other so as to vary the pressure applied to the sheet by the first and second conditioning rollers.

Apparatus and method for conditioning bamboo or vegetable cane fiber

One embodiment provides a cane processing assembly for use with a substantially cylindrical bamboo culm having a longitudinal axis and a plurality of nodes. The assembly comprising a feeder, a perforating station adjacent to the feeder to receive the culm, the perforating station having an annular cutter assembly with cutting blades positioned around an open central area that receives the culm. The cutting blades are radially movable between retracted and extended positions, wherein the cutting blades are positioned to cut into a node around the circumference of the culm. A splitter station receives the culm after the perforating station. The splitter station has a splitting blade configured to cut the culm along its length. A planar station adjacent to the splitter station has a plurality of rollers positioned to engage and flatten the cut culm into a planar configuration.

Apparatus and method for processing bamboo or vegetable cane

Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of antibody or portions for treating and/or diagnosing IL-12 related conditions, diseases, and disorders, such as psoriasis.

A natural fiber-based, engineered beam assembly comprising opposing top and bottom surfaces, opposing first and second side surfaces and a longitudinal axis. Loads applied to the beam assembly are normal to the top surface. Substantially parallel layers of flattened bamboo or vegetable cane culms are stacked and laminated together. Each layer is formed by at least one culm, and each culm has fiber bundles extending substantially parallel to the longitudinal axis and are impregnated with a binder. The density of the fiber bundles in the culm decreases across the culm's thickness from the exterior surface to the interior surface. At least a plurality of the culms have a common orientation, wherein the exterior surfaces face toward a same one of the top, bottom, first or second side surfaces.

Industrial products engineered from processed bamboo or vegetable cane

An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Method of treating lupus by administering an anti-IL-12 antibody

The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS:1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.

Anti-TNF antibodies, compositions, methods and uses

Anti-IL-12 antibodies and compositions

Growing community of inventors

Berwyn, PA, United States of America

David M Knight