Antares Pharma, Inc.

Other

Becton Dickinson and Company Limited

Medi-ject Corporation

David M Deboer

Paul R Lesch, Jr

Peter L Sadowski

Claude L Berman

Margaret L Holland

Lucio Giambattista

Sheldon J Nelson

A jet injection device with a fluid chamber in a housing member for holding about 0.02 ml to about 3 ml of a medicament. An injection-assisting needle has an injection end that extends from the housing for inserting into a patient to a depth of up to about 5 mm. A force-generating source is configured to apply a pressure reaching about 100-1000 psi to the medicament in the chamber to expel the medicament through the injecting end of the needle.

Needle assisted jet injector

A needle assisted jet injector and method for jet injecting medicament are disclosed. In one embodiment of the injector, the needle is retractably located within an injector nozzle assembly. Upon activation of the force generating source, a portion of the needle extends past the nozzle assembly and penetrates the outer layer of skin to deliver the medicament via jet injection to a deeper region. After activation, the needle retracts back into the nozzle assembly. In another embodiment, the needle is fixed to the end of the nozzle assembly. In both embodiments, the length of the portion of the needle that penetrates the skin is less than 5 mm.

A probe and nozzle assembly for reducing the pressure at which a needleless injector must deliver medicament for proper delivery are disclosed. In one embodiment of the probe, the probe is retractably located within an injector nozzle assembly. Upon activation of the energy source a portion of the probe extends past the nozzle assembly to deliver the medicament through a discharge channel. After activation the probe retracts back into the nozzle assembly. In another embodiment, the probe is fixed to the end of the nozzle assembly. In both embodiments the ratio of discharge channel length to diameter is greater than 6/1.

Injection-assisting probe for medical injector assembly

A probe and nozzle assembly for reducing the pressure at which a needleless injector must deliver medicament for proper delivery are disclosed. In one embodiment of the probe, the probe is retractably located within an injector nozzle assembly. Upon activation of the energy source a portion of the probe extends past the nozzle assembly to deliver the medicament through a discharge channel. After activation the probe retracts back into the nozzle assembly. In another embodiment, the probe is fixed to the end of the nozzle assembly. In both embodiments the ratio of discharge channel length to diameter is greater than 6/1. The present invention also relates to nozzle assemblies with a discharge channel length to diameter ratio greater than 6/1.

A loading mechanism for a medical injector assembly is disclosed. The loading mechanism according to the present invention includes a dosing sleeve slidingly joining first and second injector housing portions and having tabs at a first end and fixed to one of the first or second housing portions at a second end; and a sleeve retainer fixed to the other of the first or second housing portions and engageable with the tabs of the dosing sleeve at an engagement point to prevent movement of the dosing sleeve once an injector plunger is at a rear portion of an injector fluid chamber, wherein movement of the first housing portion away from the second housing portion moves the plunger in a second direction to load fluid into the fluid chamber and movement of the first housing portion toward the second housing portion moves the plunger in a first direction to remove the fluid from the fluid chamber. The disclosed loading mechanism facilitates filling the assembly with medicament and priming the assembly for use.

Growing community of inventors

Brighton, MI, United States of America

David M Deboer