Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

E. R. Squibb Sons, Inc.

Université Louis Pasteur

Other

David Lohnes

Pierre H Chambon

Philippe Kastner

Manuel Mark

Marianne Lemeur

Andree Dierich

Thomas Lufkin

Cathy Mendelsohn

Philippe Gorry

The present invention provides mice which are deficient in the normal expression of one or more members of the RAR or RXR class of receptors, to mice heterozygous for such deficiency, and to cell lines, preferably pluripotent or totipotent cell lines, which are heterozygous or homozygous for such deficiency. The present invention further provides the use of any of the above mice and cell lines in situations where the absence of at least one RAR or RXR receptors, or the normal expression thereof, is desirable.

Genetically engineered mice containing alterations in the genes encoding retinoic acid receptor proteins

Genetically engineered mice and cell lines containing alterations in the

Genetically engineered mice containing alterations in the genes encoding

Growing community of inventors

Montreal, Canada

David Lohnes