Labopharm Inc.

Bombardier Inc.

Paladin Labs Inc.

Paladin Labs (barbados) Inc.

Paladin Labs Europe Limited

Labopharm Europe Limited

Labopharm (barbados) Limited

Short Brothers Plc

David Lessard

Sandra Gori

Laibin Luo

Maxime Ranger

Yuan Wang

Julie Lafreniere

Jean-Francois Meunier

Genevieve Bibeau

Damon Smith

Miloud Rahmouni

Vinayak Sant

François Ravenelle

Frederic Lebrun

Lu Wei Liu

Dorothee Le Garrec

Francois Ravenelle

Dorothée Le Garrec

Geneviève Bibeau

Jean-François Meunier

The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.

Solid formulations of liquid biologically active agents

A headrest for a seat of a vehicle includes a body securable to the seat, a side portion adjacent the body, a receiver pivotally attached to the body, a slide attached to the side portion so as to be movable along the receiver between a first position in which the side portion is in a retracted position and a second position in which the side portion is in an extended position, and a friction member on one of the receiver and the slide. A securing mechanism causes the friction member to hold the slide in a selected position relative to the receiver.

Headrest with adjustable side elements

The instant invention provides a two-step polymerization process for preparing amphiphilic poly(N-vinyl-2-pyrrolidone), (PVP)-block-polyester copolymers and other diblock and triblock copolymers consisting of PVP as one block. The block copolymers of the invention can be used as vehicles for drug delivery.

Process for the preparation of amphiphilic poly(N-vinyl-2-pyrrolidone) block copolymers

Process for the preparation of amphiphilic poly (N-vinyl-2-pyrrolidone) block copolymers

Growing community of inventors

Montreal, Canada

David Lessard