Edwards Lifesciences Corporation

Other

Inari Medical, Inc.

Showdown Games, LLC

David Leigh Hauser

Jan Otto Solem

David Alon

Pui Tong Ho

David Mark Taylor

Alexander H Cooper

Tri D Tran

Robert C Taft

Sean Chow

Neil S Zimmerman

Eric R Reuland

Glen Thomas Rabito

Thomas Mills, Jr

Stanton J Rowe

Travis Zenyo Oba

Mark Chau

Emil Karapetian

Dustin P Armer

Christopher J Olson

Rafael Pintor

Donald E Bobo, Jr

Seung-Beom Yi

Stephen C Geist

Marlowe E Patterson

Cristobal R Hernandez

Seung Yi

Richard B Cates

Steve Geist

Certain aspects of the disclosure concern a device for repairing or replacing a native heart valve. The device can include a frame including a first set of struts intersecting with a second set of struts at a plurality of strut connection points. The frame can be radially expandable from a radially collapsed state to a radially expanded state. The device can include at least one expansion feature including a screw head and a screw shaft connected to the screw head. The screw shaft can extend through a first strut connection point and a second strut connection point. The device can further include a plurality of penetrating members extending from a first end of the frame. Rotating the screw shaft in a first direction can radially expand the frame from the radially collapsed state to the radially expanded state.

Cardiac valve repair devices configured for percutaneous delivery

A method is disclosed for removing a vascular occlusion, such as a clot, from a blood vessel. A tubular sheath is inserted into the vessel and a self-expanding Nitinol mesh filter is deployed from a distal end of the tubular sheath at a location proximal to a clot. An inner catheter is advanced through the tubular sheath and through the mesh filter for contacting the clot. An expandable agitation element is provided along a distal end portion of the inner catheter for cutting or chopping the clot, thereby facilitating removal of the clot and improving blood flow through the vessel. Resulting clot particles are captured by the mesh filter. Negative pressure may be applied along a proximal end portion of the sheath for aspirating remaining particles. Certain embodiments of the method are well-suited for treating deep vein thrombosis and do not require the use of thrombolytic drugs.

Method for treating vascular occlusion

A method of treating a defective heart valve includes inserting a delivery catheter through a small incision in a patient's groin, wherein the delivery catheter has a prosthetic device positioned along a distal end. The prosthetic device includes an insert member and an anchoring member. The insert member self-expands to plug gaps between leaflets of the heart valve. The anchoring member is preferably a stent connected to the insert member by at least one elongate member. The stent is deployed within an adjacent blood vessel for anchoring the insert member. After deployment of the prosthetic device, the leaflets of the heart valve form a tight seal against the insert member for preventing regurgitation when the leaflets are closed and wherein blood passes through the insert member when the leaflets are open.

Method of treating a defective heart valve

Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter. Adjustments may continue until the leaflets fully coapt and the problem of mitral regurgitation is reduced or eliminated.

A method of treating a defective heart valve includes inserting a delivery catheter through a small incision in a patient's groin, wherein the delivery catheter has a prosthetic device positioned along a distal end. The prosthetic device includes an insert member and an anchoring member. The insert member is positioned between the native heart valve and is allowed to self-expand. The anchoring member is preferably a stent connected to the insert member by at least one elongate member. The stent is deployed within an adjacent blood vessel for anchoring the insert member between the native leaflets. After deployment of the prosthetic device, the native leaflets of the heart valve form a tight seal against the insert member for preventing regurgitation through the native heart valve during ventricular systole.

A card game system/method pitting players against a live or virtual dealer. Players make two mandatory wagers and optionally place bonus and jackpot wagers followed by each player and the dealer receiving six cards. Each player and the dealer must set the six cards into three, two-card hands based on pre-established rules. The main and play wagers are resolved based on a comparison of the player's three hands to the dealer's three hands, respectively. The bonus wager relates to the strongest five-card poker hand formed using the six cards and the jackpot is paid if the player wins all three hands and the two cards of the first hand meet a minimum threshold (e.g., Ace high or better). An automatic winning hand may be utilized as well. For example, any player receiving the King of Spades and King of Clubs would win their main and play wagers automatically. A player v. player (e.g., home version) version of the game is also disclosed.

Casino game system and method of use

A method of treating a defective mitral valve includes inserting a delivery catheter through a small incision in a patient's groin, wherein the delivery catheter has a prosthetic device positioned along a distal end thereof. The prosthetic device includes an insert member and an anchoring member, wherein the insert member is made from a shape memory material and is surrounded by a biocompatible fabric outer layer. The insert member is positioned within a mitral valve and self-expands in a gap between the native leaflets. The anchoring member is attached to surrounding tissue. After deployment of the prosthetic device, the native leaflets of the mitral valve form a tight seal against the biocompatible fabric outer layer and the insert member fills the gap between the native leaflets of the mitral valve for preventing regurgitation during ventricular systole.

Method of treating a defective mitral valve by filling gap

A system for mechanically capturing and removing a thrombus from a blood vessel includes a flexible guidewire adapted to contact the thrombus in the blood vessel, an aspiration catheter, an elongate catheter, and a self-expanding body fixedly attached to a distal end portion of the elongate catheter. The self-expanding body extends distally from the elongate catheter for capturing the thrombus. The self-expanding body preferably has a proximal end portion with a tapered shape and an open distal end. The self-expanding body is permeable for allowing blood to pass through the self-expanding body and into the central lumen of the aspiration catheter. The system may further include a thrombolytic drug to help dissolve the thrombus before capturing the thrombus with the self-expanding body.

System for removing a thrombus from a blood vessel

A method of capturing and removing a thrombus from a large vein is performed using a percutaneous thrombectomy device. The thrombectomy device includes a delivery sheath, a filter body, and an inner catheter provided with an agitation member. The sheath is advanced until a distal end is positioned proximal to the thrombus. The filter body is deployed distal to the sheath and proximal to the thrombus. The filter body preferably has a funnel shape with a tapered proximal end portion and an open distal end. The inner catheter is advanced through the sheath for contacting the thrombus with the agitation member. The agitation member is actuated to disrupt the thrombus. Thrombus particles are captured using the filter body and negative pressure is preferably applied through the sheath. The method is well-suited for treating deep vein thrombosis and does not require the use of thrombolytic drugs.

Method of removing a thrombus from a large vein

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Newport Beach, CA, United States of America

David Leigh Hauser