Other

Baylor College of Medicine

David L Nelson

C Thomas Caskey

Stephen T Warren

Maura Pieretti

Ben A Oostra

Arnold Munnich

Richard A Lewis

Annemarie Poustka

Alain Israel

Nina Heiss

Michele D'Urso

Jennifer Kelly Heine Clemmons

Asmae Smahi

Swaroop Aradhya

Hayley Woffendin

Moise Levy

Sue J Kenwrick

Ying-hui Fu

A workshop community includes a plurality of standalone workshop structures positioned around a central building. Each workshop within the community is individually owned, with workshop owners jointly owning the central building and associated infrastructure such a paths, fences and lights. Each workshop includes multiple doors, an individual electrical meter, parking, and gate access. The central building is the administrative and social hub of the workshop community.

Separately owned workshops with shared central building

Incontinentia Pigmenti (IP) is a neurocutaneous genodermatosis that segregates as an X-linked dominant disorder with a high probability of prenatal male lethality. A locus in Xq28 containing NF-&kgr;B Essential Modulator, a gene product involved in the activation of NF-kB and central to many pro-inflammatory and apoptotic pathways, contains mutations in the majority of cases of IP. Disclosed are methods, compositions and kits directed to a defect in a NF-&kgr;B related disease such as IP.

Diagnosis and treatment of medical conditions associated with defective NFkappa B(NF-&kgr;B) activation

A sequence of the FMR-1 gene is disclosed. This sequence and related probes, cosmids and unique repeats are used to detect X-linked diseases and especially the fragile X syndrome. Also, methods using methylation-sensitive restriction endonuclease and PCR primer probes were used to detect X-linked disease.

Diagnosis of the fragile X syndrome

A sequence of the FMR-1 gene is disclosed. This sequence and related probes, cosmids and unique repeats are used to detect X-linked diseases and especially the fragile X syndrome.

Growing community of inventors

Houston, TX, United States of America

David L Nelson