Duke University

David L Epstein

Mitchell Anthony deLong

Eric John Toone

Ronald F Overaker

Brian C Dodge

Xin Chen

Pratap Challa

Molly Walsh

Phillip W Snyder

Stuart McKinnon

Paul P Lee

Vasanth Rao

The present disclosure provides an elastomeric material for the delivery of an ophthalmic agent to the eye of a subject and methods of using such material.

Ophthalmic drug delivery device and methods of use

The present invention relates generally to ophthamological drugs. More specifically, the invention relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma.

Ophthamological drugs

The present invention relates, in general, to glaucoma and, in particular, to a method of preventing or treating glaucoma using statins.

Method of preventing or treating glaucoma

The present invention relates, in general, to methods of treating disorders of the eye, and, in particular, to methods of preventing or treating elevated eye pressure and glaucoma. The invention further relates to compounds and compositions suitable for use in such methods.

Method of treating disorders of the eye

A dispensing cap including a rotary valve communicating with an external open-ended dispensing tube portion, the valve being configured to communicate, in a venting position, with a venting pathway and to communicate, in a dispensing position, with an internal dispensing tube portion, wherein the valve is configured to pass from a closed position through a venting position to a dispensing position.

Automatically-venting dispensing cap

The present invention relates, in general, to methods of treating disorders of the eye, and, in particular, to methods of preventing or treating elevated eye pressure and glaucoma by administering to a patient in need thereof a non-sulfhydryl reactive derivative of phenoxyacetic acid (eg indacrinone or ticrynafen) that increases aqueous humor outflow. The invention further relates to compounds and compositions suitable for use in such methods.

Growing community of inventors

Bahama, NC, United States of America

David L Epstein