Novo Nordisk A/s

David John McConnell

Steen Troels Jo Slashedrgensen

Catherine M Buckley

Audrey Hobson

Charles O'Kane

Boerge Krag Diderichsen

Kevin Martin Devine

The present invention relates to an expression system which comprises a phage-like bacteriocin('phibacin') or a mutant thereof, or a gene or mutant of a phibacin having a function in gene expression, such as a repressor gene, which is used to transform bacterial host for the producion of proteins, in particular in gram positive bacteria.

Gene expression system

A process for producing an active lipase enzyme in vitro, comprising mixing an inactive or partly active lipase enzyme with a chaperone molecule and subjecting the mixture to denaturation followed by renaturation to produce the active lipase enzyme.

Process for preparing lipases

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Dublin, Ireland

David John McConnell