Warner-lambert Company

Pfizer Corporation

David James Dooley

David Juergen Wustrow

Andrew John Thorpe

Charles Price Taylor, Jr

Thomas Gary Heffner

Ann Elizabeth Corbin

Hyacinth Chi Akunne

Alysia Latrese Green

Mark John Field

Richard Griffith Williams

This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by administering a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein: Ris hydrogen, straight or branched alkyl of from 1 to 6 carbon atoms or phenyl; and Ris straight or branched alkyl of from 4 to 8 carbon atoms, straight or branched alkenyl of from 2 to 8 carbon atoms, cycloalkyl of from 3 to 7 carbon atoms, alkoxy of from 1 to 6 carbon atoms, -alkylcycloalkyl, -alkylalkoxy, -alkyl OH, -alkylphenyl, -alkylphenoxy, or -substituted phenyl. The invention also relates to a method of treating the above disorders by administering the compound (3S,5R)-3-Aminomethyl-5-methyl-octanoic acid.

Alpha 2 delta ligands for post-traumatic stress disorder

This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by administering a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein:

Alpha2delta ligands for fibromyalgia and other disorders

The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formula and pharmaceutically acceptable salts thereof, wherein Ris hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.

Method of treating tinnitus

The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formulaand pharmaceutically acceptable salts thereof, wherein Ris hydrogen or straight or branched lower alkyl, and n is an integer of from 4 to 6.

Cyclic amino acids, such as gabapentin and pregabalin, are used for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants and other addictive drugs/substances. Physiological conditions include stimulant-induced toxicities.

Methods for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants

Known cyclic amino acids, such as gabapentin and pregabalin, are used for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants and other addictive drugs/substances. Physiological conditions include stimulant-induced toxicities.

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South Lyon, MI, United States of America

David James Dooley