Target Therapeutics, Inc.

Boston Scientific Scimed, Inc.

Prolifix Medical, Inc.

Iscience Interventional Corporation

Ams Research Corporation

Astora Women's Health, LLC

Iscience Surgical Corporation

Other

Lumend, Inc.

Bioconnect Systems, Inc.

David J Kupiecki

Son M Gia

Chaouki A Khamis

Hong Doan

Stanley R Conston

John R McKenzie

Mehran Bashiri

Shawn Michael Wignall

Erik T Engelson

Joseph Charles Eder

Clifford Teoh

Uriel Hiram Chee

Ivan Sepetka

Ronald G Williams

Jeffrey J Christian

U Hiram Chee

Michael J Mariant

Pete Phong Pham

Greg R Patterson

Jeffrey M O'Hern

Kathy M Mah

John Mckenzie

John Fritz Otte

Gary A Rocheleau

Richard C Kaleta

Gregory L Koeller

James D Passafaro

Jeffrey Michael O'Hern

Benjamin J Clark

Marc-Alan Levine

Ronald Kenichi Yamamoto

Neil J Sheehan

Matthew R Selmon

John Ortiz

James J Leary

Meir H Moshe

Aaron J Miller

Robert Christopher Stegmann

Brent Seybold

Sergio Salinas

Kurt Sparks

Thuzar K Han

Cong Thach

Timothy B McFann

Richard Kaleta

Roger W Perkins

Joan Huynh

Candice Danielle Pinson

Michael D Keleher

Candice D Pinson

Ron K Yamamoto

Jeffrey L Emery

C Danielle Pinson

Allen W Madsen

Candice D Seybold

John R Mckenzie

Jeffrey Michael O'hern

Chaouki Ahmad Khamis

Jeffrey M O'hern

Ronald K Yamamoto

Robert Stegmann

Candice Pinson

Described are implants, tools, and methods useful for treating pelvic conditions such as prolapse, by placing an implant to support pelvic tissue, the implants, tools, and methods involving one or more of adjusting engagements, specific implants and pieces of implants, placement of implants at locations within the pelvic region, and insertion, adjusting, and grommet management tools.

Pelvic floor treatments and related tools and implants

Described are implants, tools, and methods useful for treating pelvic conditions such as prolapse, by placing an implant to support pelvic tissue, the implants, tools, and methods involving one or more of an insertion tool that works in coordination with a sheath, adjusting engagements, specific implants and pieces of implants, placement of implants at locations within the pelvic region, and insertion, adjusting, and grommet management tools.

Pelvic or other types of implants are provided that can include tensioning feedback components or portions, such as color changing polymer materials, such as polyacetylene. The color changing polymer can be included with, coated on or otherwise provided with a portion of slings or implant devices to provide targeted feedback to the user or physician of the tension applied to a particular device. A first color can be used to indicate a first (initial) tension or compression stage, and a second color can be used to indicate tensioning of the device beyond a predefined threshold.

Implant systems with tensioning feedback

Microcannulae are constructed with multiple components in a composite design, allowing the microcannulae to have varying mechanical and delivery properties that will enable ophthalmic treatments by minimally invasive means. The microcannula includes at least one flexible, tubular communicating element with an outer diameter of 350 microns or less, a proximal connector for introduction of materials, energy or tools. It may also include a reinforcing member attached to the communicating element, which may be designed to create variable stiffness along the length of the microcannula. The microcannula may also include other features such as a signal beacon near the distal tip.

Composite ophthalmic microcannula

A method is provided for increasing the outflow of fluid through Schlemm's canal that is useful for treatment of glaucoma. The implant is placed in Schlemm's canal by use of a flexible delivery instrument attached to the implant. The instrument and implant are positioned within the canal, the implant is released and the distal and proximal ends of the implant are connected to apply sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability. In another embodiment a delivery instrument attached to the implant is positioned in the canal securing one of the distal or proximal ends of the implant within the canal. The implant provides sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability of the inner wall of the canal. The other of the distal or proximal ends may be secured to maintain the tensioning force on the inner wall of the canal.

Ophthalmic implant for treatment of glaucoma

An injector is provided to deliver microquantities of viscous materials into the body, such as the eye, for surgical purposes. The injector comprises a syringe body with a plunger disposed therein coupled to a positive displacement mechanism capable of progressively advancing the plunger to precisely deliver microquantities of materials at a constant or predetermined delivery rate.

Injector for viscous materials

The present invention provides devices and associated methods for delivering side-to-side and end-to-side anastomotic connectors to join any two (or more) vessels together such that fluid communication is established between the lumens of the two or more joined vessels. The systems of the present invention employ one or more deployment mechanisms over which the anastomotic connector is positioned for delivery and subsequently deployment within a vessel. The deployment mechanisms may be inflatable balloons or expandable baskets or a combination thereof or the like, which, when inflated and/or expanded, cause one or more portions of the anastomotic connector to deploy.

Devices and methods for interconnecting body conduits

A catheter system and corresponding methods are provided for accessing a blood vessel true lumen from a sub-intimal plane of the vessel. The catheter system includes visualization elements for determining the orientation of the true lumen with respect to the sub-intimal plane at an identified entry site from a position in the sub-intimal plane. The entry site is distal to a chronic total occlusion (CTO). The catheter system also includes a system for physically securing tissue of the sub-intimal plane at the entry site to the catheter system. The attaching system reduces or eliminates catheter float within the sub-intimal space. The catheter system further includes re-entry devices to establish and maintain a path from the sub-intimal plane back into the vessel true lumen.

Catheter system for vascular re-entry from a sub-intimal space

This is a medical catheter made up of a body having on its distal end portion an expandable balloon and, proximal of the balloon, a delivery lumen ending in a port through which therapeutic or diagnostic agents may be delivered. In one variation, a single inflation/wire lumen extends from the catheter proximal end to the catheter distal end, through which the balloon is inflated with pressurized fluid and through which a guide wire extends. The guide wire may have a valve plug for selectively seating against a valve seat of the catheter distal end to seal the inflation/wire lumen for balloon inflations. In another variation, a vaso-occlusive agent is disposable within a delivery lumen in a catheter coupled with a steerable guidewire. The delivery lumen ends in a delivery port near to and proximal of an expandable balloon located at the catheter's end. A single inflation/wire lumen may also be provided for facilitating both balloon inflation and guide wire tracking.

Balloon catheter with delivery side holes

Growing community of inventors

San Francisco, CA, United States of America

David J Kupiecki