Plasmology4, Inc.

Tc13-pressure Applications LLC

Tci3—pressure Applications LLC

Continuous Motionflow, LLC

Technology Capital Investors, LLC

Cold Plasma Medical Technologies, Inc.

David J Jacofsky

Marc C Jacofsky

Gregory A Watson

Robert M Hummel

John P Peeters

Roy Werner Sanders

Frank S Silveira

Jeffrey I Meyers

Mark W Smithers

Alan A Waldman

Jeffrey Lyman

Systems and methods for monitoring pressure exerted on an individual at one or more points by a support structure and adjusting the support structure in response to the monitored pressure are disclosed. The method for monitoring pressure may include the step of periodically receiving with at least three radio frequency readers, localized contact pressure data from a radio frequency addressable sensor placed on an individual. The method may further include, when an adjustment is required, calculating a radial distance defining a radius of the radio frequency addressable sensor to the at least three radio frequency readers, and calculating an intersection location or overlap of the radii such that the location of the radio frequency addressable sensor is determined. The method may also include, when the location of the radio frequency addressable sensor is determined, adjusting cells within a zone or subzone corresponding to the location.

Systems and methods for monitoring and providing therapeutic support for a user

Embodiments of a compartment monitor that can be implanted and left in situ to continuously (or semi-continuously) measure compartment pressures are presented. An exemplary monitor includes a pressure sensor adapted to be implanted in a compartment, a transmitter external to the compartment and coupled to the pressure sensor, and a receiver in communication with the transmitter to receive and process pressure data received from the transmitter. The monitor may also be configured to transmit measured pressure data to a networkable device. The networkable device can then communicate the patient's status and condition to a healthcare provider through a local area network (LAN) or wide area network (WAN). This communication allows the healthcare provider to remotely monitor a patient. The networkable device, or associated computing system, can record and display trends in the pressure data over time, and log the data to the patient's electronic health records.

Compartment syndrome monitoring systems and methods

A compact cold plasma device for generating cold plasma having temperatures in the range 65 to 120 degrees Fahrenheit. The compact cold plasma device has a magnet-free configuration and an induction-grid-free configuration. An additional configuration uses an induction grid in place of the input electrode to generate the cold plasma. A high voltage power supply is provided that includes a controllable switch to release energy from a capacitor bank to a dual resonance RF transformer. A controller adjusts the energy input to the capacitor bank, as well as the trigger to the controllable switch.

Cold plasma treatment devices and associated methods

A cold plasma helmet application device for delivery of cold plasma benefits to the head of a patient. An appropriate gas is introduced into a helmet receptacle within a containment dome of the helmet. The gas is energized by one or more dielectric barrier devices that receive energy from a pulsed source. The dielectric barrier devices can be configured to match the treatment area. Such a device and method can be used to treat large surface areas treatment sites associated with the head, head trauma, brain cancer, the control of brain swelling with closed head injury or infection, as well as treating male pattern baldness.

A method and device to apply a cold plasma to a substance at a treatment surface of a patient to cause electroporation of the substance into cells of the patient. The substance can be previously applied to the treatment surface. Alternatively, the substance can be placed in a foam-like material within a tip that passes the cold plasma from the cold plasma device to the treatment area. The tip can be a cannula device with an aperture at the distal end. The cannula device can also have apertures along a portion of the length of the cannula device.

Cold plasma electroporation of medication and associated methods

The present disclosure relates to methods of treating diseases and disorders comprising applying a therapeutically effective dose of cold plasma. In particular examples, the diseases and disorders include, but are not limited to, diseases and disorders of the skin, musculoskeletal, and immune systems.

Therapeutic applications of cold plasma

A nozzle for attachment to a cold plasma device configured to maintain delivery of a stable cold plasma. The nozzle can have many different shaped apertures to support different applications requiring different shaped cold plasma plumes. Use of a disc of foam material within a nozzle can expand the size of aperture of a nozzle while maintaining delivery of a stable cold plasma. The nozzle can be an elongated cannula tube for internal delivery of a cold plasma treatment. The cannula tube can provide an aperture at its distal end or one or more apertures along its length. A shroud can partially enclose the distal aperture of the nozzle. A sterile sleeve can be used in conjunction with a nozzle to provide a sterile means of attachment and operation of the nozzle with a cold plasma device. In addition, various shaped apertures may be deployed to provide selective targeting of the cold plasma to a treatment area, while shielding other biological structures from cold plasma exposure. Such apertures also provide an opportunity for manual manipulation of tissues in the treatment area prior to or during cold plasma treatment.

Harmonic cold plasma devices and associated methods

A system including a wearable cold plasma system, including a wearable cold plasma applicator configured to couple to and deliver a cold plasma to a surface of a user wearing the wearable cold plasma device.

Wearable cold plasma system

A cold plasma mask application device for delivery of a cold plasma to the face of a patient. An appropriate gas is introduced into a gas containment area that is energized by one or more electrodes that receive energy from a pulsed source. The plasma can be prevented from contact with the patient's face, or can be allowed to make contact with the patient's face at the appropriate treatment area. A three-layer approach to the manufacture of the cold plasma mask application device is also described. Such a device and method can be used to treat acne as well as complex facial wounds such as those resulting from trauma, melanoma, and other cancers of the face, rosacea, and psoriasis.

A method for monitoring pressure at one or more points on an individual and automatically adjusting one or more sections of a support structure. The method includes periodically receiving pressure data from one or more radio frequency addressable sensors placed on an individual; determining, based on the received pressure data, whether an adjustment in the support structure is required; systematically adjusting cells located within the plurality of zones, one zone at a time, until an improvement in pressure data is indicated. If an improvement in pressure data is indicated for a zone, systematically adjusting cells within the plurality of subzones for that zone, one subzone at a time, until an improvement in pressure data is indicated. If an improvement in pressure data is indicated for a subzone, systematically adjusting cells in that subzone, one cell at a time, until an improvement in pressure data is indicated.

Growing community of inventors

Peoria, AZ, United States of America

David J Jacofsky