Takeda San Diego, Inc.

Takeda Pharmaceutical Company Limited

Takeda California, Inc.

David J Hosfield

Robert J Skene

Jeffrey Alan Stafford

Alexei Brooun

Sheng Ye

Michael Brennan Wallace

Qing Dong

Stephen L Gwaltney

Zhiyuan Zhang

Sheldon Cao

Nicholas Scorah

Bheema Rao Paraselli

Leslie William Tari

Kathleen Aertgeerts

Jun Feng

Ellen Chi

Mingnam Tang

Yan Liu

Sridhar Govinda Prasad

Beverly Lynn Wolgast

Mark Knuth

Douglas R Dougan

Mark Hilgers

Ciaran N Cronin

Prasuna Guntupalli

Yasuhisa Kohara

Bi Ching Sang

Duncan E McRee

Robert A Wijnands

Oleg Brodsky

Hidehisa Iwata

Yanming Zhang

Sheldon X Cao

Bheema R Paraselli

Beverly Throop

Compounds, pharmaceutical compositions and kits are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.

Kinase inhibitors

Compounds, pharmaceutical compositions, kits and methods are provided for use with glucokinase that comprise a compound selected from the group consisting of formula (I) wherein the variables are as defined herein. 

Imidazopyridine compounds

Compounds are provided for use with hexokinases that comprise: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.

Substituted indazoles as glucokinase activators

Provided are crystals relating to Farsenyl Pvrophosphate Synthase (IspA) fromand its various uses.

Crystalline composition of farsenyl pyrophosphate synthase (IspA)

Provided are crystals relating to DPPIV and its various uses.

Crystallization of dipeptidyl peptidase IV (DPPIV)

Provided are crystals relating to MvaS (HMG-CoA Synthase) and its various uses.

Crystallization of MvaS (HMG-CoA Synthase)

Provided are crystals relating to 11-Beta-Hydroxysteroid Dehydrogenase type 1 and its various uses.

Crystallization of 11-Beta-Hydroxysteroid Dehydrogenase type 1

Provided are structure coordinates relating to MvaS and its various uses.

Crystal structure of MvaS

Growing community of inventors

Solana Beach, CA, United States of America

David J Hosfield