Abbott Laboratories Corporation

Other

Abbvie Inc.

Icahn School of Medicine at Mount Sinai

Abb Vie Deutschland Gmbh & Co. Kg

David J Hawksworth

Robert N Ziemann

Bryan C Tieman

Susan E Brophy

Bailin Tu

Joan D Tyner

Larry G Birkenmeyer

A Scott Muerhoff

Christopher C Marohnic

Mary S Pinkus

Kathy Otis

April Ahlberg

Robert William Siegel

Carol S Ramsay

Anthony Scott Muerhoff

Dinesh O Shah

Barry Lee Dowell

Cheng Zhao

Carolyn J Strobel

Philip M Hemken

Michael White

Saul A Datwyler

Frank C Grenier

Robert E Dubler

James W Scheffel

Frank S Ungemach

Robin A Gutierrez

Jonathan Grote

Daniel S Nam

Dominick L Pucci

Sharmila Manoj

Jeffrey M Werneke

Larry K Wray

Hal D Hopkins

Gregg A Hadley

Mary P Frintner

Zhiguang Yu

Suresh M Desai

Bernhard K Mueller

Qiaoqiao Ruan

Sergey Y Tetin

Ryan F Workman

Andreas Popp

Elaine Marie Brate

Gangamani S Beligere

Edward T Olejniczak

Andrea Branch

Jessie W Shih

Lowell J Tyner, Legal Representative

David J Daghfal

Matthew S Matias

Michael J Beggs

Francis Eng

Stephen C Hsu

Don M Laird

Linda J Sohn

Robert J Herrmann

Don C Laird

David J Dagfal

David C Sogin

Lianli Chi

Shamila Manoj

Joan D(deceased) Tyner

Bryan Tieman

Barry L Dowell

The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies. In certain embodiments, the lipid binding domain monoclonal antibody recognizes an epitope in amino acids 141 to 161 of HCV core protein.

Detection methods employing HCV core lipid and DNA binding domain monoclonal antibodies

Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.

Anti-GP73 monoclonal antibodies and methods of obtaining the same

The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.

The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of

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The present invention relates to monoclonal antibodies for the detection of HCV antigen. More specifically, the invention describes antibodies against HCV core antigen lipid binding domain and immunoassay methods, kits and compositions for use in detecting HCV infection.

HCV core lipid binding domain monoclonal antibodies

Provided herein are antibodies and methods of using the antibodies to treat, prevent, modulate, attenuate and diagnose iron-related disorders.

Composition and method for the diagnosis and treatment of iron-related disorders

The present invention relates to antibodies specific for glycosylated mammalian NGAL, and to methods of making and using such antibodies.

Antibodies that bind to mammalian NGAL and uses thereof

The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.

PlGF-1 assay and kits and components thereof

Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.

Recombinant antibodies against hepatitis C virus and methods of obtaining and using same

Growing community of inventors

Lake Villa, IL, United States of America

David J Hawksworth