Mayo Foundation for Medical Education and Research

Wayne State University

David I Smith

David Alan Ahlquist

William Russell Taylor

Hongzhi Zou

Jonathan J Harrington

Patrick S Quint

Harold R Bergen, Iii

Lily A Jones

Roy S Sundick

Harold S Bergen, Iii

George Vasmatzis

Andrew L Feldman

Ahmet Dogan

Mark Law

Zou Hongzhi

Harold R Iii Bergen

This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.

Detecting neoplasm

This document relates to the activity of interferon regulatory factor 4 (IRF4) in T-cell lymphomas. For example, methods and materials involved in reducing the expression of an IRF4 polypeptide in T-cell lymphoma cells and identifying agents having the ability to reduce expression of an IRF4 polypeptide in T-cell lymphoma cells are provided. This document also relates to reducing DUSP22 or FLJ43663 polypeptide activity in T-cell lymphomas. For example, methods and materials involved in reducing the expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells and identifying agents having the ability to reduce expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells are provided.

Reducing IRF4, DUSP22, or FLJ43663 polypeptide expression

The present invention pertains to isolated DNA encoding avian interleukin-15 and to purified interleukin-15 polypeptides.

Chicken interleukin-15 and uses thereof

Growing community of inventors

Rochester, MN, United States of America

David I Smith