Ucl Business Plc

Galvani Bioelectronics Limited

General Electric Company

The University of Sydney

University of Cape Town

Cyqiq Ltd

David Holder

Kirill Aristovich

Daniel John Chew

Matteo Donega

Rizwan Bashirullah

Gerald Edwin Hunsberger

Jonathan Craig Tapson

Andre Van Schaik

Simon Robert Arridge

Emma Rosa Malone

Gustavo Sato Dos Santos

Alistair Lee McEwan

Thomas Dowrick

A nerve stimulation system including at least one nerve interface device is disclosed. The device includes a cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the cuff portion, each ring of electrodes including a plurality of electrodes, and wherein each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The system includes a stimulation device in communication with the pairs of electrodes to generate different electrical signals for the pairs of electrodes and a control system that causes the different signals to causes different physiological responses.

Nerve stimulation device for current steering

A nerve interface device including at least one cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the at least one cuff portion, each ring of electrodes including a plurality of electrodes. Each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The plurality of pairs of electrodes includes at least a first pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion. The at least one cuff portion includes an asymmetric configuration about a central axis perpendicular to the longitudinal cuff axis.

Nerve stimulation device for unidirectional stimulation and current steering

There is provided a nerve activity monitoring method that includes receiving an input signal indicative of activity in a nerve of a subject; receiving physiological data indicative of physiological activity in the subject; establishing a relationship between the physiological data and the input signal; identifying a plurality of periodic portions in the input signal based on the relationship between the physiological data and the input signal; and outputting the periodic portions identified.

Nerve activity monitoring

There is disclosed a method of determining electrical properties in a peripheral nerve of a human or animal subject using a plurality of electrodes spaced around a perimeter of the nerve, by applying a probe electrical signal to each of a plurality of combinations of the electrodes, and using the resulting electrical responses to determine the electrical properties, for example by carrying out an electrical impedance tomography image reconstruction.

Detecting activity in peripheral nerves

Approaches are disclosed for electrical impedance tomography which apply a current to a region at two or more frequencies and acquire voltage measurements at each frequency to generate a set of multi-frequency voltage measurements. One or more images of the region are generated, using spectral constraints, based on the multi-frequency data.

Method and system for tomographic imaging

A method is provided for taking electrical impedance tomography measurements using multiple electrodes located at selected positions external to a volume of a subject body. Multiple orthogonal or near-orthogonal signals are introduced simultaneously by way of selected different electrodes and resultant predetermined responses (if any) at receiving electrodes are recorded or determined. The signals are encoded using the technique of code division multiplexing and received signals at each receiving electrode are cross-correlated with original signals to determine the contribution of each original signal to a composite received signal. The invention also relates to apparatus suitable for use in applying a method.

System and method for conducting multiplexed electrical impedance tomography

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London, United Kingdom

David Holder