Vero Biotech Inc.

Geno LLC

The Coca-cola Company

Thermo Electron Corporation

L-3 Communications Cyterra Corporation

Thermedics Inc.

Cyterra Corporation

Thermedics Detection, Inc.

Other

Sony Corporation

Sony Electronics Inc

Thermo Fisher Scientific Gmbh

L-3 Communications Security and Detection Systems Corporation

Thermolase Corporation

David R. Rounbehler

David H Fine

David P Rounbehler

Gregory Vasquez

Bryan J Johnson

Stephen J MacDonald

Freeman W Fraim

David R Rounbehler

Ryan Denton

Eugene K Achter

Lucas G Gamero

Edward E A Bromberg

William Steinway

Edward Bromberg

George Jarvis

Jonathan L Rolfe

Herbert A Duvoisin, Iii

Thorsten Schmidt

Ravi K Konduri

David B Wheeler

Gregory Stilwell

David P Lieb

Helmut W Klotzsch

Joshua Hopkins

Barry N Gellman

Alex Malaspina

Daniel B Dennison

Eddie R Tajudeen

Kenneth M Thrash, Jr

Forrest Lee Bayer

James E Wicks

Sean Christiansen

C Andrew Helm

Alf L Carroll

Jody Fuller

Paul Crabb

Dirck vanBuren Myers

Geoffrey Solomon

George B Jarvis

Brian Johnson

Alessandra Miranda

Steven Bullock

Marjorie Nelson

Stephen J Macdonald

David Wheeler

Nikolai I Tankovich

Clayton D Wood

Lewis J Rubin

Eric J Moy

Edward E Bromberg

Robert Frank Roscigno

Douglas O Carlson

Dirk Appel

Lynn W Noble

John S Beaty

Paul W Fairchild

Daniel J O'Donnell

Eugenie Hainsworth

James B McGown

Michel D Arney

Zhong-Quan Zhao

Kurt A Dasse

John J Fronduto

Daniel A Dussault

Mark Fraser

Gregory J Wendell

Stephen Cole

Vladimir G Kolinko

John Lee, Jr

Mike Lefebvre

James E Buckley

Kevin Johnson

Tammy Watts

Elizabeth Bartosz

Neil Alan Stewart

Yarelis M Rios

John M Oelschlaeger

W Fraim Freeman

Stephen E O'Brien

Freemand W Fraim

Greg Vasquez

Dirck Van Buren Myers

Lee Leichter

Yuriy Pylypenko

Ronald D Ross, Jr

A Lindsay Carroll, Jr

Eddie Tajudeen

Brian J Johnson

Steve Cole

Jason White

Doug Sonosky

Francis A Di Bella

Amanda J Reynolds

Allen Hunter, Ii

Susan Murrell

Lucas Gamero

Ed Bromberg

Bryan Johnson

Robert F Roscigno

A device and method for calibrating a NO delivery device using NO and NOmeasurements, without using a known standard.

Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards

A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid NOactivate upon operator demand, convert NOto NOvia a heating element(s) controlled by a console to deliver NOat a controlled flow rate, direct concentrated NOto a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.

Nitrogen dioxide storage device

A device and method for treating high-altitude sickness can include a handheld device, and can deliver a therapeutic amount of nitric oxide to an individual's lungs in order to minimize or treat high-altitude sickness. The device is self-contained and portable, which allows an individual to carry and use the device in high-altitude or other low-oxygen environments.

Apparatus and method for portable nitric oxide delivery

Dinitrogen tetroxide (NO) is synthesized in an apparatus by the reaction of concentrated nitric acid with copper. Oxygen is applied as a carrier gas to convert NO to NO, and water vapor is removed with a tube dryer. A molecular sieve is applied to reduce and remove impurities.

Method and apparatus for manufacturing nitrogen tetroxide

Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.

Systems and devices for generating nitric oxide

A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

Conversion of nitrogen dioxide (NO) to nitric oxide (NO)

A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.

Nitric oxide therapies

Various systems, devices, NOabsorbents, NOscavengers and NOrecuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.

A device and method for calibrating a delivery device includes providing a container A containing a nitrite, providing a container B containing an acid, releasing the contents of containers A and B, allowing the nitrite and acid to mix, waiting for a predetermined time, allowing air to combine with the mixture, and using NO and traces of NOto check and calibrate NO and NOsensors.

Method and apparatus for automatic calibration

Start-up protocols for a device and method for administering NO is described.

Start-up protocols for nitric oxide delivery device

A system for delivering a therapeutic amount of nitric oxide can include a reservoir containing a nitrogen dioxide source. A heating element can be configured to heat the reservoir, causing nitrogen dioxide vapor to exit the reservoir through a restrictor into a conduit. The nitrogen dioxide vapor can mix with gas from a gas supply, which can then flow to a cartridge that includes a surface-activated material saturated with an aqueous solution of a reducing agent. The cartridge can convert the nitrogen dioxide into nitric oxide.

Delivery of ultra pure nitric oxide (NO)

Growing community of inventors

Cocoa Beach, FL, United States of America

David H Fine