Boston Scientific Scimed, Inc.

Medtronic, Inc.

Barosense, Inc.

Ventrica, Inc.

David H Cole

Daniel J Balbierz

Andrew C Smith

Samuel T Crews

Darin Charles Gittings

Bretton Mark Swope

Dean F Carson

Mark J Foley

Pablo R Hambly

Keke Lepulu

Jason S Stewart

A Adam Sharkawy

Michael Lawrence Reo

Carlos Castro

Adam Kessler

J Greg Stine

Adam Sharkawy

Tyler Grubb

Craig A Purdy

Hollie Pope

Amador Hallare

John P Lunsford

Alan R Rapacki

Gilbert S Laroya

Wally S Buch

Jesica Ferro

Stephen L Olson

Sam Crews

Justen Deering England

Fiona Maria Sander

Brett Swope

Melanie L Harris

Devices and methods for acquiring and fastening tissues folds within an internal organ, such as the stomach, and for applying the methods and devices to producing reductions in organ volume or repair of bariatric procedures, are disclosed. An exemplary method for forming a continuous laterally extending tissue fold involves forming a succession of laterally extending folds having adjacent overlapping fold portions. One exemplary tissue-acquisition device has an open-end roller-and-arm structure that allows individual tissue folds to be formed and fastened, then advanced to an adjacent region within the stomach, for capture of a new fold that will form an extension of the existing fold(s).

Tissue-acquisition and fastening devices and methods

A staple housing includes an array of staples each in a staple delivery position or 'ready position' ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.

Multi-fire stapling systems and methods for delivering arrays of staples

An endoscopic stapler is disclosed. The stapler includes a staple member and an anvil member. The staple member may include a staple housing and the staple holder may include one or more staples. The anvil member may be spaced apart from the staple member and may configured to relatively move towards one another. A controller may be fluidly coupled to the staple member through a plurality of conduits. The controller may be configured to (a) direct a pressurized fluid to the staple member through a first conduit of the plurality of conduits to relatively move the staple member and the anvil member towards one another, and (b) direct the pressurize fluid through a second conduit of the plurality of conduits to eject one or more staples from the staple holder.

System for controlling a tissue-stapling operation

A stapling device for forming multiple tissue plications without needing to reload the device between plications is described. The device includes staple and anvil housings that move toward and away from a tissue-capture position. A cartridge holder in the staple housing supports a cartridge with multiple groups of offset staple slots, where the slots in each group are circularly arrayed about a cartridge center axis. A staple driver in the staple housing carries a plurality of arms for engaging and ejecting the staples in a first group of staples in the cartridge, when a tissue fold is captured between the cartridge assembly and anvil in the anvil housing. When the staple driver is retracted, after a tissue plication is formed, the cartridge assembly and tissue drive are indexed to eject the next-up group of staples.

Stapler for forming multiple tissue plications

Multi-fire stapling methods

Described herein are endoscopic plicators passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed plicators allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver sutures, staples or other means for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications is formed, medical devices may be coupled to the plication(s) for retention within the stomach.

Endoscopic plication devices and methods

Described herein is an improved device and method for acquiring, and optionally, fastening a tissue fold. The device has an improved configuration for forming a single, two-layer tissue fold.

Tissue-acquisition device and method

Described herein are endoscopic staplers and methods used to apply one or more fasteners to body tissue. In one embodiment, a fastener-applying device, which is preferably a stapler, is passed transorally into the stomach to plicate stomach tissue by engaging tissue from inside the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn into a tissue chamber, causing sections of serosal tissue to be positioned facing one another. The disclosed staplers allow opposed sections of tissue to be moved into contact with another, and preferably deliver staples for maintaining contact between tissue sections at least until serosal bonds form. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention, After one or more plications are formed, medical devices may optionally be coupled to the plication(s) for retention within the stomach.

Endoscopic stapling devices

This application describes an overtube device that gives diagnostic and/or therapeutic access to body cavities using natural orifices of the body. The overtube includes an elongate flexible body having a distal portion deflectable in response to activation of a control cable. Proximal features of the overtube include an insufflations port and seals for minimizing loss of insufflations pressure around the shafts of instruments passed through the tube. In some embodiments, retractor elements are including on the distal portion of the overtube.

Overtube introducer for use in endoscopic bariatric surgery

A staple housing includes an array of staples each in a staple delivery position or 'ready position' ready to be fired into target tissue. A staple driver is advanceable to drive the ready position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.

Multi-fire stapling systems

In a method of stapling layers of tissue within a body cavity, an engaging instrument is passed between a stapler cartridge and anvil and used to engage a region of tissue. The engaging instrument is retracted to move the engaged tissue into the stapling position, and driving staples from the cartridge through at least two layers of the engaged tissue. The method and associated system may be used to form plications in body tissue, such as stomach wall tissue. Staples simultaneously driven through tissue may simultaneously capture a reinforcing elements positioned adjacent the cartridge and/or anvil prior to stapling.

Endoscopic plication device and method

Growing community of inventors

San Mateo, CA, United States of America

David H Cole