Other

Duke University

Shubin, Steven A., Sr.

David H Ashley

Steven A Shubin, Sr

Anthony Barlow

Steven A Shubin, Jr

Philip V D'Andrea

Steven A Shubin

Darell D Bigner

Matthias Gromeier

Smita K Nair

Philip V D'andrea

Anthony A Barlow

Steven A Shubin Sr

Philip V D'ANDREA

Steven A Shubin Jr

Creating a replica of an anatomical structure. In one embodiments a method includes: accepting pictures of the anatomical structure of a subject; creating an object file that contains an initial model of an outside surface of the anatomical structure; cutting the initial model to a predetermined exterior shape circumscribing the anatomical structure to create a positive model; creating a negative model from the positive model; placing a stem tool object on an outside surface of the negative model in relationship to an orifice, thereby creating a final negative model; placing a zeroing and angling object to align the negative model to a predetermined angle; placing a base tool object by coupling the base tool object to the outside surface; printing, by way of a three-dimensional printer, the final negative model to create a negative mold; and casting the replica of the anatomical structure using the negative mold.

Method and system of creating a replica of an anatomical structure

Methods of testing tumor samples for mutational burden and/or for expression profiles permit the prediction of responsiveness of an individual to immunotherapy comprising PVSRIPO. Those predicted to respond are treated with PVSRIPO and those predicted not to respond are treated with other agents.

Methods for predicting tumor response to immunotherapy

Creating a replica of an anatomical structure. At least some of the example embodiments are methods including: accepting a plurality of pictures of the anatomical structure of a subject; creating an object file that contains an initial model of an outside surface of the anatomical structure; cutting the initial model to a predetermined exterior shape circumscribing the anatomical structure, the cutting creates a positive model of the anatomical structure within the predetermined exterior shape; creating a negative model of the anatomical structure from the positive model; placing a stem tool object on an outside surface of the negative model in relationship to an orifice of the anatomical structure, and thereby creating a final negative model; printing, by way of a three-dimensional printer, the final negative model to create a negative mold; and casting the replica of the anatomical structure using the negative mold.

Growing community of inventors

Austin, TX, United States of America

David H Ashley