The Cleveland Clinic Foundation

Volcano Corporation

David Geoffrey Vince

Anuja Nair

Kendall Rand Waters

Jon D Klingensmith

Marja Pauliina Margolis

Barry D Kuban

Raj Shekhar

Marja Paulina Margolis

Russell J Fedewa

Hesham A Elsharkawy

A system includes a processor and, a computer-readable tangible storage device storing program instructions for execution by the processor. The program instructions include instructions for receiving ultrasonic derived data comprising an ultrasound image, representing a region of interest, and radio frequency '(RF') data associated with the ultrasound image, and instructions for analyzing the RF data to identify at least one feature associated with a region of interest, including either or both of a feature representing a two-dimensional spectrum feature and a feature based on a cepstrum determined from the RF data. The program instructions further include instructions for classifying the region of interest as one of a plurality of anatomical classes from the identified at least one feature and causing a display to display the anatomical class.

Advanced ultrasonic detection of different tissue types

A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.

Plaque characterization using multiple intravascular ultrasound datasets having distinct filter bands

A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto&#x2014;e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure. The backscattered data is then transmitted to the computing device, where it is used to estimate the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue (e.g., identify tissue type, etc.).

System and method for determining a transfer function

An intravascular ultrasound (IVUS) analysis system and method is provided which determines luminal and medial-adventitial boundaries of a blood vessel. Ultrasonic data is acquired by a rotating transducer mounted to a tip of a catheter which is inserted into the blood vessel. An intravascular image is reconstructed from the ultrasound data. To determine the luminal boundary of a vessel, a user selects boundary points on the image believed to be locations of the luminal boundary. A boundary contour is generated based on the boundary points. The boundary contour is then optimized by adjusting the boundary points based on a radially determined edge of the luminal boundary performed on the image in polar format. Once the final luminal boundary contour is generated, the process is repeated to determine the medial-adventitial boundary contour. With the contour data, properties of the blood vessel are analyzed including determining the area of the lumen and percent of occlusion caused by plaque.

Intravascular ultrasonic analysis using active contour method and system

Growing community of inventors

Avon Lake, OH, United States of America

David Geoffrey Vince