University of Glasgow

Equine Virology Research Foundation

David Edward Onions

Lesley Nicolson

The present invention involves isolated equine herpesvirus-4 (EHV-4) or gH or gC polypeptides and antigenic fragments. Methods of using the polypeptides and the fragments thereof are also presented.

EHV-4 gH or gC glycoprotein polypeptides and methods of use

An Equine herpesvirus-4 (EHV-4) mutant which does not produce a functional thymidine kinase due to a deletion and/or insertion in the gene encoding thymidine kinase, the deletion and/or insertion made at a position within the thymidine kinase gene such as to not substantially alter expression of the UL24 gene. Recombinant DNA comprising DNA of the EHV-4 mutant, host cells containing the recombinant DNA, and a process for the preparation of the EHV-4 mutant.

Equine herpesvirus-4TK mutant

The present invention involves isolated nucleic acid molecules encoding the equine herpesvirus-4 (EHV-4) gH or gC polypeptide, the polypeptides so encoded, and antigenic fragments thereof. Vectors and host cells containing these nucleic acid sequences, and uses thereof, are presented.

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Glasgow, United Kingdom

David Edward Onions