Koninklijke Philips Corporation N.V.

Cyberonics, Inc.

Neurovista Corporation

Other

Agilent Technologies, Inc.

David E Snyder

Kent W Leyde

Thomas D Lyster

John F Harris

Carlton B Morgan

Bradford Evan Gliner

Daniel J Powers

Kim J Hansen

Hans Patrick Griesser

Thomas Allen Solosko

Eric L Jonsen

Javier Ramón Echauz

Gust H Bardy

Jon Mikalson Bishay

Cecily Anne Snyder

Tom Lyster

Carl Morgan

An automated external defibrillator (AED) is described which spends an increased proportion of a rescue in a CPR mode. This is accomplished by use of a single shock protocol which causes the AED to spend less time in shock analysis and delivery activities as compared with the typical multiple shock protocol. An AED of the present invention preferably is configured such that the rescue protocol can be modified or changed easily without the need to remove the battery or use specialized hardware or software. Preferably the shock waveform of the single shock is a biphasic waveform delivering at least 150 Joules of energy and more preferably at least 200 Joules of energy.

Automatic external defibrillator with increased CPR administration time

Automated external defibrillator with increased CPR administration time

An automated external defibrillator (AED) is described which spends an increased proportion of a rescue in a CPR mode. This is accomplished by use of a single shock protocol which causes the AED to spend less time in shock analysis and delivery activities as compared with the typical multiple shock protocol. An AED of the present invention preferably is configured at the factory with a single shock protocol as the default rescue protocol. The rescue protocol can be modified or changed easily without the need to remove the battery or use specialized hardware or software. Preferably the shock waveform of the single shock is a biphasic waveform delivering at least 175 Joules of energy and more preferably at least 200 Joules of energy.

The invention provides a method of monitoring a subject's neurological condition. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition, such as by activating a green light or other visible output. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition. The invention also provides neurological system monitors.

Systems and methods for identifying a contra-ictal condition in a subject

A defibrillator having a pair of electrodes for delivering an artifact-compensated defibrillation shock and a method thereof is provided. The defibrillator can be deployed rapidly while administering a cardio-pulmonary resuscitation (CPR) on the patient. Upon detection of an end of the CPR operation, a correlation signal indicative of signal corruption is detected and analyzed rapidly to determine an appropriate energy level discharged across the pair of electrodes. Thereafter, a notification signal is sent to the user of the defibrillator prior to delivering the defibrillation shock to the patient. The artifact-compensated defibrillation shock is delivered if for a predetermined period of time no movement is detected.

External defibrillator with shock activated by cessation of precordial compressions

Systems and methods of monitoring a subject's neurological condition are provided. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition. The systems and methods may utilize a minimally invasive, leadless device to monitor the subject's condition. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition.

Implantable systems and methods for identifying a contra-ictal condition in a subject

A defibrillator having a pair of electrodes for delivering an artifact-compensated defibrillation shock and a method thereof is provided. The defibrillator can be deployed rapidly while administering a cardio-pulmonary resuscitation (CPR) on the patient. Upon detection of an end of the CPR operation, a correlation signal indicative of signal corruption is detected and analyzed rapidly to determine an appropriate energy level discharged across the pair of electrodes. Thereafter, a notification signal is sent to the user of the defibrillator prior to delivering the defibrillation shock to the patient. The artifact-compensated defibrillation shock is delivered if for a predetermined period of time no movements is detected.

Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.

Processing for multi-channel signals

Methods of classifying a subject's condition are described. The method includes: receiving measured signals from the subject; processing the measured signals using a computing device to identify a class associated with an identified condition of the subject; introducing an artificial class, the artificial class being associated with an unknown condition of the subject; classifying a feature vector from the subject into the identified class or the artificial class; and generating a signal in response to classifying the feature vector. The measured signals from the subject may include at least one signal extracted from brain activity of the subject.

Classification of patient conditions using known and artificial classes

Systems and methods for enhancing the accuracy of classifying a measurement by providing an artificial class. Seizure prediction systems may employ a classification system including an artificial class and a user interface for signaling uncertainty in classification when a measurement is classified in the artificial class.

Reduction of classification error rates and monitoring system using an artificial class

An electrode includes a conductive adhesive layer and a conductive foil layer having a void therein. One such electrode may be mounted in conjunction with another electrode upon a release liner having one or more openings therein to facilitate electrical signal exchange between electrodes. A release liner may include a moisture permeable and/or moisture absorbent membrane. A release liner may alternatively include a conductive backing layer. A release liner may also include an insulating swatch covering an opening. A release liner may be implemented as a foldable sheet, such that multiple electrodes may be mounted upon the same side of the foldable sheet. A medical device to which the mounted electrodes are coupled may characterize the electrical path between the electrodes. The medical device may perform a variety of electrical measurements, including real and/or complex impedance measurements. Based upon one or more measurements, the medical device may provide an indication of electrode condition, fitness for use, and/or an estimated remaining lifetime. An electrode condition indicator, which may form a portion of the medical device, may generate, present, or display electrode condition and/or estimated remaining lifetime information via a visual metaphor, such as a fuel gauge.

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Bainbridge Island, WA, United States of America

David E Snyder