Thermo Finnigan LLC

David E Minkler

Eloy R Wouters

Joshua A Silveira

Michael L Poltash

Raman Mathur

Michael G Konicek

Thi Le

Dale Lindseth

Determining a level of a liquid in a container is described. In one aspect, a container includes a calibrant liquid used for calibrating a mass spectrometer. A conductive layer is placed to float upon the calibrant liquid, and a circuit board with electrodes is arranged around the container. A controller circuit then drives and measures various electrodes to first identify which two electrodes the level of the calibrant liquid is between, and then subsequently identify a more precise location for the level between the two electrodes.

Mass spectrometery calibrant liquid container level sensing

An electrospray ionization system used in mass spectrometry provides for improved current measurement. The system includes a fluid union, a fluid column coupled with a first port of the fluid union, a power source coupled with the fluid union and configured to apply a voltage potential to the fluid union, and an electrospray emitter coupled with a second port of the fluid union. The power source is coupled with the first port and configured to apply the voltage potential to the first port to restrict current leakage from the fluid union. The current sensing circuit is configured to determine an electrical current flow between the power source and the at least one of the fluid union and the first port.

Electrospray current measurement in the nanospray and microspray regime

This technology is directed to a method and apparatus for monitoring or testing defects associated with an ion lens connected within a mass spectrometer. In some implementations, the testing mechanism monitors a connection of one or more ion lenses configured in the mass spectrometer to determine if voltage is effectively applied to the ion lens. The testing circuit of the present technology includes at least one Zener diode added to the voltage divider and monitoring a change in slope of the applied voltage versus the voltage at the read-back circuit. The change in slope may be easily measured.

Method and apparatus for monitoring ion lens connections

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Campbell, CA, United States of America

David E Minkler