Radisens Diagnostics Limited

David Doolan

Donal Cronin

Gregory John Kellogg

Jerry O'Brien

Eoin O'Nuallain

Fabio Miguel Rolo Pereira

Yan Zhao

The invention provides a microfluidic system comprising a cartridge coupled to a motor and adapted to move a fluid sample to a plurality of locations on the cartridge. The cartridge comprises a chevron shaped or substantially V shaped reaction chamber having at least three zones, a first zone positioned near the apex of the V shaped reaction chamber to define a detection zone, a second zone positioned near a first end of the V shaped reaction chamber and a third zone positioned near a second end of the V shaped reaction chamber. The motor and a control module is configured to provide a combination of centrifugal force and gravitational force to move said fluid sample between at least three zones.

Point-of-care diagnostic assay cartridge

A microfluidic system for processing biological samples comprising a holding chamber adapted for holding a fluid and to be rotated on a platform, said holding chamber comprising an outlet through which fluid flow is controlled by an acceleration-primed valve system, wherein the acceleration-primed valve system comprises a capillary valve and an outlet channel. The invention provides a novel valving system, which retains fluids at low angular velocities, removes the need for hydrophilic surfaces, minimises disc real-estate and optimises certain microfluidic processes done in the holding chamber.

Acceleration-primed valving system for centrifugal microfluidics

The invention relates to a microfluidic system for processing biological samples comprising a transfer pipette; a platform adapted to provide at least one receiving chamber and configured to receive said transfer pipette, and a distal output chamber wherein a biological sample from the transfer pipette is dispensed into the output chamber when a centrifugal force is applied.

Growing community of inventors

Tullamore, Ireland

David Doolan