Dsm IP Assets B.v.

Roche Vitamins Inc.

Ciba Specialty Chemicals Corporation

David Carl Burdick

Werner Bonrath

Ingo Koschinski

Andrew George Gum

Elena Muelchi

Isabelle Prevot-Halter

Heinz Egger

Thomas Netscher

Bernard Orsat

Frank Schager

Andreas Thum

Dominik Thomas

Peter Schirg

Stefan Bischof

Sai-Shek Young

Stuart Frank Laermer

A process for the manufacture of (all-rac)-&#x3b1;-tocopherol comprises submitting isolated, purified phytyltrimethylhydroquinone to acid catalysis, thereby promoting ring closure to (all-rac)-&#x3b1;-t-tocopherol. The process can be conducted in the absence or presence of an added solvent, and when a solvent or solvent mixture is used the solvent or at least one solvent component of the solvent mixture is preferably one with a dipole moment greater than 9&#xd7;10C-m (or 2.7D). The nature of the catalyst is immaterial, but the catalyst is preferably sulphuric acid, phosphoric acid, a polyperfluoroalkylenesulphonic acid, a 'NH-acid', a heteropoly acid, zinc chloride, boron trifluoride, aluminium trichloride, or a mixture of any f the aforementioned Br&#xf6;nsted acids with any of the aforementioned Lewis acids. The product of the process is the most active an industrially most important member of the vitamin E group.

Manufacture of &#x3b1;-tocopherol

A process is provided for making (&#x2212;)-epigallocatechin gallate (EGCG) by subjecting a green tea extract to chromatography on a macroporous polar resin, eluting EGCG from the resin with a polar elution solvent, optionally concentrating the eluate, optionally regenerating the resin by desorbing the remaining catechins, and optionally concentrating the desorbed catechins.

Process for the production of (&#x2212;)-epigallocatechin gallate

The invention relates to a process for the preparation of 2H-isoflavones which process comprises the reaction of a 2-hydroxyaryl alkyl ketone in the presence of a base with a formic-sulfuric anhydride salt which reaction is followed by neutralization. The procedure is especially suitable for the preparation of genistein.

Process for the preparation of isoflavones

The present invention is a process for concentrating aqueous epigallocatechin gallate (EGCG) solutions by feeding an aqueous EGCG solution to at least one membrane module under pressure to provide a permeate purge and a retentate return so that in the latter the concentration of EGCG is increased. The permeate purge and the retentate return are then collected.

Process for concentrating epigallocatechin gallate

The invention provides a process for the manufacture of a retinyl acylate of the formula I:

Manufacture of cycloalkenylpolyene esters

A stabilizing system for plastic materials is disclosed. This system comprises a homogenous blend of alpha-tocopherol, optionally together with other additives and a polyolefin carrier which is a free flowing solid form. The free flowing solid form is easy to incorporate into plastic materials.

Stabilizer composition for thermoplastic materials

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Binningen, Switzerland

David Carl Burdick