Warner-lambert Company

Auckland Uniservices Limited

David C Ware

William Alexander Denny

William Robert Wilson

Brian Desmond Palmer

Graham John Atwell

Ralph James Stevenson

Jared Bruce Milbank

William P Wilson

This invention relates to a class of heterocycles and their metal complexes, and is particularly concerned with the use of these compounds in the preparation of prodrugs or as prodrugs that may be activated under hypoxic conditions by enzymes or by therapeutic ionising radiation, in the treatment of cancer. The invention also relates to the use of these heterocycles and the corresponding metal complexes in the preparation of medicaments and to compositions including the heterocycles or their metal complexes and to methods for preparing these compounds.

Anti-cancer 2,3-dihydro-1H-pyrrolo[3,2-f]quinoline complexes of cobalt and chromium

New cobalt complexes of nitrogen mustard alkylating agents which have been found to have hypoxia-selective antitumor properties and are thereby useful antitumor agents are described.

Cobalt complexes as anticancer agents

New cobalt complexes of nitrogen mustard alkylating agents which have been found to have hypoxia-selective antitumour properties and are thereby useful antitumour agents are described.

Cobalt complexes as anti-cancer agents

Growing community of inventors

Auckland, New Zealand

David C Ware